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Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8pk8
Q-score: 0.661
Schulz V, Steinhilper R, Oltmanns J, Freibert SA, Krapoth N, Linne U, Welsch S, Hoock MH, Schunemann V, Murphy BJ, Lill R
Nat Commun (2024) 15 pp. 3269-3269 [ DOI: doi:10.1038/s41467-024-47310-8 Pubmed: 38627381 ]
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Acyl carrier protein (8 kDa, Protein from Escherichia coli BL21(DE3))
- Lyr motif-containing protein 4 (13 kDa, Protein from Homo sapiens)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Cysteine desulfurase (44 kDa, Protein from Homo sapiens)
- Iron-sulfur cluster assembly enzyme iscu (15 kDa, Protein from Homo sapiens)
- Frataxin mature form (14 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Iron-bound human nfs1-isd11-acp1-iscu2-fxn (fe-niaux) complex during persulfide transfer (Complex from Homo sapiens)
- Fe (ii) ion (55 Da, Ligand)
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 8pk9
Q-score: 0.661
Schulz V, Steinhilper R, Oltmanns J, Freibert SA, Krapoth N, Linne U, Welsch S, Hoock MH, Schunemann V, Murphy BJ, Lill R
Nat Commun (2024) 15 pp. 3269-3269 [ DOI: doi:10.1038/s41467-024-47310-8 Pubmed: 38627381 ]
- Cysteine desulfurase (44 kDa, Protein from Homo sapiens)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Acyl carrier protein (8 kDa, Protein from Escherichia coli BL21(DE3))
- Lyr motif-containing protein 4 (13 kDa, Protein from Homo sapiens)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Iron-sulfur cluster assembly enzyme iscu (15 kDa, Protein from Homo sapiens)
- Frataxin mature form (14 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Iron-bound human nfs1-isd11-acp1-iscu2-fxn (fe-niaux) complex during persulfide transfer (Complex from Homo sapiens)
- Fe (ii) ion (55 Da, Ligand)
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8pka
Q-score: 0.624
Schulz V, Steinhilper R, Oltmanns J, Freibert SA, Krapoth N, Linne U, Welsch S, Hoock MH, Schunemann V, Murphy BJ, Lill R
Nat Commun (2024) 15 pp. 3269-3269 [ DOI: doi:10.1038/s41467-024-47310-8 Pubmed: 38627381 ]
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Iron-bound human nfs1-isd11-acp1-iscu2-fxn (fe-niaux) complex during persulfide transfer (Complex)
- Lyr motif-containing protein 4 (13 kDa, Protein from Homo sapiens)
- Acyl carrier protein (8 kDa, Protein from Escherichia coli BL21(DE3))
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Cysteine desulfurase, lyr motif-containing protein 4 and iron-sulfur cluster assembly enzyme iscu (Complex from Homo sapiens)
- Cysteine desulfurase (44 kDa, Protein from Homo sapiens)
- Acyl carrier protein (Complex from Escherichia coli BL21(DE3))
- Water (18 Da, Ligand)
- Fe (ii) ion (55 Da, Ligand)
- Iron-sulfur cluster assembly enzyme iscu (15 kDa, Protein from Homo sapiens)
Resolution: 4.08 Å
EM Method: Single-particle
Fitted PDBs: 8r8q
Q-score: 0.411
To Be Published
- Glycosylated lysosomal membrane protein (43 kDa, Protein from Mus musculus)
- Glmp-mfsd1 (Complex from Mus musculus)
- Major facilitator superfamily domain-containing protein 1 (55 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM Structure of CdnG-E2 complex from Serratia marcescens (UltrAuFoil)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8hsb
Q-score: 0.38
Yan Y, Xiao J, Huang F, Xian W, Yu B, Cheng R, Wu H, Lu X, Wang X, Huang W, Li J, Oyejobi GK, Robinson CV, Wu H, Wu D, Liu X, Wang L, Zhu B
Nat Microbiol (2024) [ DOI: doi:10.1038/s41564-024-01684-z Pubmed: 38649411 ]
- Cdng-e2 binary complex (Complex from Serratia marcescens)
- Cdng (45 kDa, Protein from Serratia marcescens)
- Type vi secretion protein (18 kDa, Protein from Serratia marcescens)
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8jle
Q-score: 0.517
Yamagata A, Ito K, Suzuki T, Dohmae N, Terada T, Shirouzu M
Nat Commun (2024) 15 pp. 3027-3027 [ DOI: doi:10.1038/s41467-024-47322-4 Pubmed: 38637505 ]
- Synaptic vesicle glycoprotein 2a (12 kDa, Protein from Homo sapiens)
- Sv2a in complex with bont/a2 hc domain and anti-epileptic drug, levetiracetam (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Botulinum neurotoxin (49 kDa, Protein from Clostridium botulinum)
Cryo-EM structure of SV2A in complex with BoNT/A2 Hc
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8jlg
Q-score: 0.551
Yamagata A, Ito K, Suzuki T, Dohmae N, Terada T, Shirouzu M
Nat Commun (2024) 15 pp. 3027-3027 [ DOI: doi:10.1038/s41467-024-47322-4 Pubmed: 38637505 ]
- Sv2a ld4 in complex with bont/a2 hc domain from the sv2a-bont/a2 hc complex (Complex from Homo sapiens)
- Synaptic vesicle glycoprotein 2a (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Botulinum neurotoxin (49 kDa, Protein from Clostridium botulinum)
Cryo-EM structure of a Legionella effector complexed with actin and AMP
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8jo3
Q-score: 0.618
Zhou XT, Wang XF, Tan JX, Zhu YQ
To Be Published
- Calcium ion (40 Da, Ligand)
- Cryo-em structure of a legionella effector complexed with actin and amp (Complex from Legionella sainthelensi)
- Substrate of the dot/icm secretion system (50 kDa, Protein from Legionella sainthelensi)
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)