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Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 tetrameric complex
Resolution: 7.86 Å
EM Method: Single-particle
Fitted PDBs: 8h33
Q-score: 0.07
Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L
Nat Struct Mol Biol (2024) 31 pp. 336-350 [ Pubmed: 38332366 DOI: doi:10.1038/s41594-023-01182-6 ]
- Kelch repeat and btb domain-containing protein 2 (71 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-3 (90 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1 (13 kDa, Protein from Homo sapiens)
- Kbtbd2-cul3-rbx1 tetrameric complex (Complex from Homo sapiens)
Cryo-EM Structure of the KBTBD2-CUL3-Rbx1-p85a dimeric complex
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 8h36
Q-score: 0.068
Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L
Nat Struct Mol Biol (2024) 31 pp. 336-350 [ Pubmed: 38332366 DOI: doi:10.1038/s41594-023-01182-6 ]
- Kelch repeat and btb domain-containing protein 2 (71 kDa, Protein from Homo sapiens)
- Kbtbd2-cul3-rbx1-p85a dimeric complex (Complex from Homo sapiens)
- Phosphatidylinositol 3-kinase regulatory subunit alpha (83 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-3 (89 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1 (12 kDa, Protein from Homo sapiens)
Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 8h38
Q-score: 0.078
Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L
Nat Struct Mol Biol (2024) 31 pp. 336-350 [ Pubmed: 38332366 DOI: doi:10.1038/s41594-023-01182-6 ]
- Kbtbd2-crl3~n8 dimer assemble with csn(mutate) monomer (Complex from Homo sapiens)
- Cop9 signalosome complex subunit 6 (36 kDa, Protein from Homo sapiens)
- Csn subunit1, kbtbd2, cullin-3, rbx1 (Complex)
- E3 ubiquitin-protein ligase rbx1 (12 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 5 (37 kDa, Protein from Homo sapiens)
- Nedd8 (8 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 1 (59 kDa, Protein from Homo sapiens)
- Nedd8 (Complex)
- Cop9 signalosome complex subunit 2 (51 kDa, Protein from Homo sapiens)
- Kelch repeat and btb domain-containing protein 2 (71 kDa, Protein from Homo sapiens)
- Cullin-3 (89 kDa, Protein from Homo sapiens)
- Csn (Complex)
- Cop9 signalosome complex subunit 3 (47 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cop9 signalosome complex subunit 7b (29 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 4 (46 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 8 (23 kDa, Protein from Homo sapiens)
Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex
Resolution: 7.51 Å
EM Method: Single-particle
Fitted PDBs: 8h3a
Q-score: -0.024
Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L
Nat Struct Mol Biol (2024) 31 pp. 336-350 [ Pubmed: 38332366 DOI: doi:10.1038/s41594-023-01182-6 ]
- Kbtbd2, cullin-3, rbx1 (Complex)
- Cop9 signalosome complex subunit 6 (36 kDa, Protein from Homo sapiens)
- Kelch repeat and btb domain-containing protein 2 (71 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1 (12 kDa, Protein from Homo sapiens)
- Cryo-em structure of the kbtbd2-crl3~n8-csn complex (Complex from Homo sapiens)
- Cop9 signalosome complex subunit 1 (59 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 2 (51 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-3 (89 kDa, Protein from Homo sapiens)
- Csn (Complex)
- Cop9 signalosome complex subunit 3 (47 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 7b (29 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 4 (46 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 5 (37 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 8 (23 kDa, Protein from Homo sapiens)
Cryo-EM Structure of the KBTBD2-CRL3-CSN complex
Resolution: 6.73 Å
EM Method: Single-particle
Fitted PDBs: 8h3f
Q-score: -0.046
Hu Y, Zhang Z, Mao Q, Zhang X, Hao A, Xun Y, Wang Y, Han L, Zhan W, Liu Q, Yin Y, Peng C, Moresco EMY, Chen Z, Beutler B, Sun L
Nat Struct Mol Biol (2024) 31 pp. 336-350 [ Pubmed: 38332366 DOI: doi:10.1038/s41594-023-01182-6 ]
- Cop9 signalosome complex subunit 6 (36 kDa, Protein from Homo sapiens)
- Kbtbd2-crl3 (Complex)
- Kelch repeat and btb domain-containing protein 2 (73 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 1 (59 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1 (13 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 2 (51 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of the kbtbd2-crl3-csn complex (Complex from Homo sapiens)
- Csn (Complex)
- Cop9 signalosome complex subunit 7b (24 kDa, Protein from Homo sapiens)
- Cullin-3 (89 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 4 (46 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 5 (37 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 3 (49 kDa, Protein from Homo sapiens)
- Cop9 signalosome complex subunit 8 (23 kDa, Protein from Homo sapiens)
PA28alpha-beta in complex with immunoproteasome
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7dr6
Q-score: 0.24
Chen J, Wang Y, Xu C, Chen K, Zhao Q, Wang S, Yin Y, Peng C, Ding Z, Cong Y
Nat Commun (2021) 12 pp. 739-739 [ DOI: doi:10.1038/s41467-021-21028-3 Pubmed: 33531497 ]
- Proteasome subunit alpha type-5 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-2 (22 kDa, Protein from Bos taurus)
- Proteasome activator complex subunit 2 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Bos taurus)
- Proteasome activator complex subunit 1 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-10 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-8 (30 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Bos taurus)
- 20s proteasome purified from bovine spleen in complex of human pa28 (Complex from Bos taurus)
- Proteasome subunit beta type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-1 (26 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-9 (23 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-3 (23 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Bos taurus)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7dr7
Q-score: 0.448
Chen J, Wang Y, Xu C, Chen K, Zhao Q, Wang S, Yin Y, Peng C, Ding Z, Cong Y
Nat Commun (2021) 12 pp. 739-739 [ DOI: doi:10.1038/s41467-021-21028-3 Pubmed: 33531497 ]
- 20s immunoproteasome purified from bovine spleen (Complex from Bos taurus)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-2 (22 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-10 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-8 (30 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-1 (26 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-9 (23 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-3 (23 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Bos taurus)