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primary_citation_author:"Zimermann E"
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN
Release date: May 15, 2024
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- (2s)-2-[2-[4-[[(2r,3s,4s)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid (437 Da, Ligand)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
Release date: May 15, 2024
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN
Release date: May 8, 2024
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome from leishmania major (Complex from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
Release date: Oct. 11, 2023
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8a98
Q-score: 0.653
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8a98
Q-score: 0.653
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- El13_chain_i (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Small ribosomal subunit protein rack1 (34 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of leishmania major 80s ribosome snorna mutant (Complex from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis
Release date: Oct. 7, 2020
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 6zj3
Q-score: 0.548
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 6zj3
Q-score: 0.548
Matzov D, Taoka M, Nobe Y, Yamauchi Y, Halfon Y, Asis N, Zimermann E, Rozenberg H, Bashan A, Bhushan S, Isobe T, Gray MW, Yonath A, Shalev-Benami M
Nucleic Acids Res (2020) 48 pp. 11750-11761 [ Pubmed: 33091122 DOI: doi:10.1093/nar/gkaa893 ]
Sample:
- Lsu rrna chain 12 (18 kDa, RNA from Euglena gracilis)
- Ribosomal protein us3 (24 kDa, Protein from Euglena gracilis)
- Ribosomal protein el42 (10 kDa, Protein from Euglena gracilis)
- Ribosomal protein us19 (17 kDa, Protein from Euglena gracilis)
- P-trna (24 kDa, RNA from Euglena gracilis)
- 18s rrna (747 kDa, RNA from Euglena gracilis)
- Ribosomal protein ul22 (18 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 6 (75 kDa, RNA from Euglena gracilis)
- Lsu rrna chain 5 (170 kDa, RNA from Euglena gracilis)
- Ribosomal protein elegr2 (8 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 3 (37 kDa, RNA from Euglena gracilis)
- Ribosomal protein el6 (22 kDa, Protein from Euglena gracilis)
- Ribosomal protein us7 (21 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 11 (30 kDa, RNA from Euglena gracilis)
- Ribosomal protein el37 (13 kDa, Protein from Euglena gracilis)
- Ribosomal protein es28 (8 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul14 (14 kDa, Protein from Euglena gracilis)
- Ribosomal protein el13 (25 kDa, Protein from Euglena gracilis)
- Ribosomal protein el32 (16 kDa, Protein from Euglena gracilis)
- Ribosomal protein el36 (12 kDa, Protein from Euglena gracilis)
- E-trna (24 kDa, RNA from Euglena gracilis)
- Ribosomal protein el34 (14 kDa, Protein from Euglena gracilis)
- Ribosomal protein elegr3 (7 kDa, Protein from Euglena gracilis)
- Rack1 (34 kDa, Protein from Euglena gracilis)
- Water (18 Da, Ligand)
- Ribosomal protein es12 (15 kDa, Protein from Euglena gracilis)
- Ribosomal protein es27 (9 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 2 (113 kDa, RNA from Euglena gracilis)
- Ribosomal protein el21 (18 kDa, Protein from Euglena gracilis)
- Ribosomal protein us5 (27 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 9 (52 kDa, RNA from Euglena gracilis)
- Ribosomal protein us11 (16 kDa, Protein from Euglena gracilis)
- Ribosomal protein us13 (17 kDa, Protein from Euglena gracilis)
- 5.8s rrna (52 kDa, RNA from Euglena gracilis)
- Lsu rrna chain 1 (42 kDa, RNA from Euglena gracilis)
- Ribosomal protein us8 (14 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul24 (16 kDa, Protein from Euglena gracilis)
- Ribosomal protein es6 (31 kDa, Protein from Euglena gracilis)
- Ribosomal protein es19 (16 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul4 (41 kDa, Protein from Euglena gracilis)
- Ribosomal protein el41 (4 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul23 (18 kDa, Protein from Euglena gracilis)
- Ribosomal protein es31 (17 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul3 (46 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul15 (17 kDa, Protein from Euglena gracilis)
- 60s ribosomal protein l7a (32 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul5 (21 kDa, Protein from Euglena gracilis)
- Ribosomal protein el22 (18 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul13 (24 kDa, Protein from Euglena gracilis)
- 5s rrna (38 kDa, RNA from Euglena gracilis)
- Ribosomal protein el24 (17 kDa, Protein from Euglena gracilis)
- Ribosomal protein el39 (6 kDa, Protein from Euglena gracilis)
- Ribosomal protein el29 (13 kDa, Protein from Euglena gracilis)
- Ribosomal protein elegr1 (7 kDa, Protein from Euglena gracilis)
- Ribosomal protein el27 (15 kDa, Protein from Euglena gracilis)
- Ribosomal protein el31 (17 kDa, Protein from Euglena gracilis)
- Ribosomal protein el15 (24 kDa, Protein from Euglena gracilis)
- Ribosomal protein el14 (25 kDa, Protein from Euglena gracilis)
- A-site trna (3 kDa, RNA from Euglena gracilis)
- Ribosomal protein el43 (12 kDa, Protein from Euglena gracilis)
- Ribosomal protein es21 (10 kDa, Protein from Euglena gracilis)
- Ribosomal protein es30 (7 kDa, Protein from Euglena gracilis)
- Ribosomal protein el38 (9 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 4 (225 kDa, RNA from Euglena gracilis)
- A-trna (24 kDa, RNA from Euglena gracilis)
- Zinc ion (65 Da, Ligand)
- Ribosomal protein us17 (19 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul6 (22 kDa, Protein from Euglena gracilis)
- Ribosomal protein es4 (31 kDa, Protein from Euglena gracilis)
- Euglena gracilis 80s ribosome (Complex from Euglena gracilis)
- 60s ribosomal protein l10 (24 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul29 (14 kDa, Protein from Euglena gracilis)
- Ribosomal protein es7 (22 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 10 (20 kDa, RNA from Euglena gracilis)
- Ribosomal protein el40 (14 kDa, Protein from Euglena gracilis)
- Ribosomal protein us14 (6 kDa, Protein from Euglena gracilis)
- Ribosomal protein us9 (17 kDa, Protein from Euglena gracilis)
- Ribosomal protein us15 (17 kDa, Protein from Euglena gracilis)
- Ribosomal protein el19 (29 kDa, Protein from Euglena gracilis)
- Ribosomal protein es1 (28 kDa, Protein from Euglena gracilis)
- Ribosomal protein es10 (17 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul18 (29 kDa, Protein from Euglena gracilis)
- Ribosomal protein us10 (13 kDa, Protein from Euglena gracilis)
- Ribosomal protein es8 (35 kDa, Protein from Euglena gracilis)
- Ribosomal protein es17 (16 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 7 (240 kDa, RNA from Euglena gracilis)
- Ribosomal protein el20 (21 kDa, Protein from Euglena gracilis)
- Ribosomal protein us12 (15 kDa, Protein from Euglena gracilis)
- Ribosomal protein el33 (13 kDa, Protein from Euglena gracilis)
- Ribosomal protein us2 (29 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 13 (27 kDa, RNA from Euglena gracilis)
- Ribosomal protein el18 (21 kDa, Protein from Euglena gracilis)
- Ribosomal protein es25 (13 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul2 (28 kDa, Protein from Euglena gracilis)
- Ribosomal protein eseug1 (32 kDa, Protein from Euglena gracilis)
- Ribosomal protein es26 (13 kDa, Protein from Euglena gracilis)
- Ribosomal protein ul30 (28 kDa, Protein from Euglena gracilis)
- Lsu rrna chain 8 (199 kDa, RNA from Euglena gracilis)
- Ribosomal protein es24 (16 kDa, Protein from Euglena gracilis)
- Ribosomal protein us4 (22 kDa, Protein from Euglena gracilis)
- Ribosomal protein el30 (12 kDa, Protein from Euglena gracilis)