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Hantaan virus-like particle glycoprotein lattice.
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ
Mbio (2021) 12 pp. e0253120-e0253120 [ Pubmed: 34225492 DOI: doi:10.1128/mBio.02531-20 ]
Hantaan virus-like particle glycoprotein spike in complex with Fab fragment HTN-Gn1.
Resolution: 19.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7nrh
Q-score: 0.05
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ
Mbio (2021) 12 pp. e0253120-e0253120 [ Pubmed: 34225492 DOI: doi:10.1128/mBio.02531-20 ]
- Fab fragment htn-gn1 light chain (22 kDa, Protein from Oryctolagus cuniculus)
- Hantaan orthohantavirus (Virus from Hantaan orthohantavirus)
- Envelope polyprotein (40 kDa, Protein from Hantaan orthohantavirus)
- Fab fragment htn-gn1 heavy chain (24 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM structure of human ACE2 receptor bound to protein encoded by vaccine candidate BNT162b1
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7l7f
Q-score: 0.517
Vogel AB, Kanevsky I, Che Y, Swanson KA, Muik A, Vormehr M, Kranz LM, Walzer KC, Hein S, Guler A, Loschko J, Maddur MS, Ota-Setlik A, Tompkins K, Cole J, Lui BG, Ziegenhals T, Plaschke A, Eisel D, Dany SC, Fesser S, Erbar S, Bates F, Schneider D, Jesionek B, Sanger B, Wallisch AK, Feuchter Y, Junginger H, Krumm SA, Heinen AP, Adams-Quack P, Schlereth J, Schille S, Kroner C, de la Caridad Guimil Garcia R, Hiller T, Fischer L, Sellers RS, Choudhary S, Gonzalez O, Vascotto F, Gutman MR, Fontenot JA, Hall-Ursone S, Brasky K, Griffor MC, Han S, Su AAH, Lees JA, Nedoma NL, Mashalidis EH, Sahasrabudhe PV, Tan CY, Pavliakova D, Singh G, Fontes-Garfias C, Pride M, Scully IL, Ciolino T, Obregon J, Gazi M, Carrion Jr R, Alfson KJ, Kalina WV, Kaushal D, Shi PY, Klamp T, Rosenbaum C, Kuhn AN, Tureci O, Dormitzer PR, Jansen KU, Sahin U
Nature (2021) 592 pp. 283-289 [ Pubmed: 33524990 DOI: doi:10.1038/s41586-021-03275-y ]
- Angiotensin-converting enzyme 2 (Complex from Homo sapiens)
- Spike glycoprotein, envelope glycoprotein fusion (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- Human ace2 receptor complexed with protein encoded by vaccine candidate bnt162b1 (Complex)
- Spike glycoprotein, envelope glycoprotein fusion (29 kDa, Protein from Human immunodeficiency virus 1)
Cryo-EM structure of protein encoded by vaccine candidate BNT162b2
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 7l7k
Q-score: 0.484
Vogel AB, Kanevsky I, Che Y, Swanson KA, Muik A, Vormehr M, Kranz LM, Walzer KC, Hein S, Guler A, Loschko J, Maddur MS, Ota-Setlik A, Tompkins K, Cole J, Lui BG, Ziegenhals T, Plaschke A, Eisel D, Dany SC, Fesser S, Erbar S, Bates F, Schneider D, Jesionek B, Sanger B, Wallisch AK, Feuchter Y, Junginger H, Krumm SA, Heinen AP, Adams-Quack P, Schlereth J, Schille S, Kroner C, de la Caridad Guimil Garcia R, Hiller T, Fischer L, Sellers RS, Choudhary S, Gonzalez O, Vascotto F, Gutman MR, Fontenot JA, Hall-Ursone S, Brasky K, Griffor MC, Han S, Su AAH, Lees JA, Nedoma NL, Mashalidis EH, Sahasrabudhe PV, Tan CY, Pavliakova D, Singh G, Fontes-Garfias C, Pride M, Scully IL, Ciolino T, Obregon J, Gazi M, Carrion Jr R, Alfson KJ, Kalina WV, Kaushal D, Shi PY, Klamp T, Rosenbaum C, Kuhn AN, Tureci O, Dormitzer PR, Jansen KU, Sahin U
Nature (2021) 592 pp. 283-289 [ Pubmed: 33524990 DOI: doi:10.1038/s41586-021-03275-y ]
Puumala virus-like particle glycoprotein spike in complex with fab fragment P-4G2.
Resolution: 13.4 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7b09
Q-score: 0.077
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ Pubmed: 33349334 DOI: doi:10.7554/eLife.58242 ]
- Heavy chain of fab fragment p-4g2 (25 kDa, Protein from Myodes glareolus)
- Light chain of fab fragment p-4g2 (23 kDa, Protein from Myodes glareolus)
- Envelope polyprotein (49 kDa, Protein from Puumala orthohantavirus)
- Puumala virus - sotkamo (Virus from Puumala virus - Sotkamo)
- Envelope polyprotein (40 kDa, Protein from Puumala orthohantavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ Pubmed: 33349334 DOI: doi:10.7554/eLife.58242 ]
Puumala virus-like particle glycoprotein lattice.
Resolution: 13.9 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7b0a
Q-score: 0.066
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ Pubmed: 33349334 DOI: doi:10.7554/eLife.58242 ]
- Envelope polyprotein (49 kDa, Protein from Puumala orthohantavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope polyprotein (40 kDa, Protein from Puumala orthohantavirus)
- Puumala orthohantavirus (Virus from Puumala orthohantavirus)