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80S rabbit ribosome stalled with benzamide-CHX
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7mdz
Q-score: 0.502
Koga Y, Hoang EM, Park Y, Keszei AFA, Murray J, Shao S, Liau BB
J Am Chem Soc (2021) 143 pp. 13473-13477 [ DOI: doi:10.1021/jacs.1c05146 Pubmed: 34403584 ]
- Ul3 (46 kDa, Protein from Rabbit)
- Mrna (3 kDa, RNA from synthetic construct)
- 60s ribosomal protein l9 (21 kDa, Protein from Rabbit)
- 40s ribosomal protein s4 (29 kDa, Protein from Rabbit)
- 40s ribosomal protein s21 (9 kDa, Protein from Rabbit)
- Es29 (6 kDa, Protein from Rabbit)
- 40s ribosomal protein s26 (13 kDa, Protein from Rabbit)
- P-site trna (24 kDa, RNA from Oryctolagus cuniculus)
- Es1 (30 kDa, Protein from Rabbit)
- Ribosomal protein l8 (28 kDa, Protein from Rabbit)
- Es30 (14 kDa, Protein from Rabbit)
- El40 (11 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Rabbit)
- 60s ribosomal protein l41 (3 kDa, Protein from Rabbit)
- Es27 (9 kDa, Protein from Rabbit)
- El32 (15 kDa, Protein from Rabbit)
- Ul22 (21 kDa, Protein from Rabbit)
- 5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
- Es12 (14 kDa, Protein from Rabbit)
- 80s rabbit ribosome stalled with benzamide-chx (4 MDa, Complex from Oryctolagus cuniculus)
- Us12 (15 kDa, Protein from Rabbit)
- N-[(1r,3s,4r,5s)-3-{(1r)-2-[(2r,4r,6s)-2,6-dihydroxypiperidin-4-yl]-1-hydroxyethyl}-4-hydroxy-1,5-dimethylcyclohexyl]benzamide (400 Da, Ligand)
- 60s ribosomal protein l27 (15 kDa, Protein from Rabbit)
- Es25 (13 kDa, Protein from Rabbit)
- Us11 (18 kDa, Protein from Rabbit)
- El42 (12 kDa, Protein from Rabbit)
- 60s ribosomal protein l29 (26 kDa, Protein from Rabbit)
- Rack1 (35 kDa, Protein from Rabbit)
- Es19 (16 kDa, Protein from Rabbit)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Rabbit)
- S10_plectin domain-containing protein (18 kDa, Protein from Rabbit)
- Us19 (17 kDa, Protein from Rabbit)
- Es7 (22 kDa, Protein from Rabbit)
- 40s ribosomal protein s24 (15 kDa, Protein from Rabbit)
- 60s ribosomal protein l14 (23 kDa, Protein from Rabbit)
- Es28 (7 kDa, Protein from Rabbit)
- 60s ribosomal protein l36 (12 kDa, Protein from Rabbit)
- El30 (12 kDa, Protein from Rabbit)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Rabbit)
- Ribosomal protein l23 (14 kDa, Protein from Rabbit)
- El21 (18 kDa, Protein from Rabbit)
- Us8 (14 kDa, Protein from Rabbit)
- 60s ribosomal protein l24 (17 kDa, Protein from Rabbit)
- Us4 (22 kDa, Protein from Rabbit)
- El31 (14 kDa, Protein from Rabbit)
- 60s ribosomal protein l10 (24 kDa, Protein from Rabbit)
- Ribosomal protein l19 (23 kDa, Protein from Rabbit)
- Us7 (22 kDa, Protein from Rabbit)
- 60s ribosomal protein l18a (20 kDa, Protein from Rabbit)
- El35 (14 kDa, Protein from Rabbit)
- El28 (15 kDa, Protein from Rabbit)
- El23 (17 kDa, Protein from Rabbit)
- Es6 (28 kDa, Protein from Rabbit)
- 60s ribosomal protein l34 (13 kDa, Protein from Rabbit)
- 40s ribosomal protein sa (32 kDa, Protein from Rabbit)
- Us15 (17 kDa, Protein from Rabbit)
- Us10 (13 kDa, Protein from Rabbit)
- Ribosomal protein l18 (21 kDa, Protein from Rabbit)
- Ribosomal protein l37 (11 kDa, Protein from Rabbit)
- Ribosomal protein s3 (26 kDa, Protein from Rabbit)
- Es17 (15 kDa, Protein from Rabbit)
- 18s rrna (602 kDa, RNA from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- Us17 (18 kDa, Protein from Rabbit)
- Es8 (24 kDa, Protein from Rabbit)
- Us9 (16 kDa, Protein from Rabbit)
- 60s ribosomal protein l7 (29 kDa, Protein from Rabbit)
- Us13 (17 kDa, Protein from Rabbit)
- El43 (10 kDa, Protein from Rabbit)
- Zinc ion (65 Da, Ligand)
- El22 (14 kDa, Protein from Rabbit)
- Ul24 (17 kDa, Protein from Rabbit)
- Ribosomal protein l15 (24 kDa, Protein from Rabbit)
- Es31 (18 kDa, Protein from Rabbit)
- 5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l27a (16 kDa, Protein from Rabbit)
- 60s ribosomal protein l38 (8 kDa, Protein from Rabbit)
- Us5 (31 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13 (24 kDa, Protein from Rabbit)
- 60s ribosomal protein l11 (20 kDa, Protein from Rabbit)
- 60s ribosomal protein l4 (47 kDa, Protein from Rabbit)
- El39 (6 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l7a (36 kDa, Protein from Rabbit)
80S rabbit ribosome stalled with CHX
Koga Y, Hoang EM, Park Y, Keszei AFA, Murray J, Shao S, Liau BB
J Am Chem Soc (2021) 143 pp. 13473-13477 [ DOI: doi:10.1021/jacs.1c05146 Pubmed: 34403584 ]
- 80s rabbit ribosome inhibited by chx (4 MDa, Complex from Oryctolagus cuniculus)