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Recombinant Mayaro virus-like particle
Kim YC, Watanabe Y, Arlen-Celina L, Song X, Stass R, Azar SR, Rossi SL, Kuemmerer BM, Crispin M, Bowden TA, Huiskonen JT, Reyes-Sandoval A
To Be Published
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=4 VLP)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7zq8
Q-score: 0.612
Kingston NJ, Grehan K, Snowden JS, Hassall M, Alzahrani J, Paesen GC, Sherry L, Hayward C, Roe A, Stephen S, Tomlinson D, Zeltina A, Doores KJ, Ranson NA, Stacey M, Page M, Rose NJ, Bowden TA, Rowlands DJ, Stonehouse NJ
mSphere (2023) 8 pp. e0056822-e0056822 [ DOI: doi:10.1128/msphere.00568-22 Pubmed: 36719225 ]
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=3* VLP)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7zqa
Q-score: 0.513
Kingston NJ, Grehan K, Snowden JS, Hassall M, Alzahrani J, Paesen GC, Sherry L, Hayward C, Roe A, Stephen S, Tomlinson D, Zeltina A, Doores KJ, Ranson NA, Stacey M, Page M, Rose NJ, Bowden TA, Rowlands DJ, Stonehouse NJ
mSphere (2023) 8 pp. e0056822-e0056822 [ DOI: doi:10.1128/msphere.00568-22 Pubmed: 36719225 ]
Rabies virus glycoprotein in complex with Fab fragments of 17C7 and 1112-1 neutralizing antibodies
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8a1e
Q-score: 0.539
Ng WM, Fedosyuk S, English S, Augusto G, Berg A, Thorley L, Haselon AS, Segireddy RR, Bowden TA, Douglas AD
Cell Host Microbe (2022) 30 pp. 1219-1230.e7 [ Pubmed: 35985336 DOI: doi:10.1016/j.chom.2022.07.014 ]
- Fab 17c7 light chain variable domain (11 kDa, Protein from Homo sapiens)
- Fab 17c7 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Fab 1112-1 heavy chain variable domain (13 kDa, Protein from Mus musculus)
- Fab 1112-1 light chain variable domain (11 kDa, Protein from Mus musculus)
- Glycoprotein (56 kDa, Protein from Rabies virus strain Pasteur vaccin)
- Rabies virus glycoprotein (chain a) in complex with fab 1112-1 (chains b and c) and fab 17c7 (chains d and e) (330 kDa, Complex from Rabies lyssavirus)
Hantaan virus-like particle glycoprotein lattice.
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ
Mbio (2021) 12 pp. e0253120-e0253120 [ Pubmed: 34225492 DOI: doi:10.1128/mBio.02531-20 ]
Hantaan virus-like particle glycoprotein spike in complex with Fab fragment HTN-Gn1.
Resolution: 19.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7nrh
Q-score: 0.05
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ
Mbio (2021) 12 pp. e0253120-e0253120 [ Pubmed: 34225492 DOI: doi:10.1128/mBio.02531-20 ]
- Fab fragment htn-gn1 heavy chain (24 kDa, Protein from Oryctolagus cuniculus)
- Hantaan orthohantavirus (Virus from Hantaan orthohantavirus)
- Fab fragment htn-gn1 light chain (22 kDa, Protein from Oryctolagus cuniculus)
- Envelope polyprotein (40 kDa, Protein from Hantaan orthohantavirus)
Puumala virus-like particle glycoprotein spike in complex with fab fragment P-4G2.
Resolution: 13.4 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7b09
Q-score: 0.077
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ Pubmed: 33349334 DOI: doi:10.7554/eLife.58242 ]
- Envelope polyprotein (49 kDa, Protein from Puumala orthohantavirus)
- Envelope polyprotein (40 kDa, Protein from Puumala orthohantavirus)
- Puumala virus - sotkamo (Virus from Puumala virus - Sotkamo)
- Heavy chain of fab fragment p-4g2 (25 kDa, Protein from Myodes glareolus)
- Light chain of fab fragment p-4g2 (23 kDa, Protein from Myodes glareolus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ Pubmed: 33349334 DOI: doi:10.7554/eLife.58242 ]
Puumala virus-like particle glycoprotein lattice.
Resolution: 13.9 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7b0a
Q-score: 0.066
Rissanen I, Stass R, Krumm SA, Seow J, Hulswit RJ, Paesen GC, Hepojoki J, Vapalahti O, Lundkvist A, Reynard O, Volchkov V, Doores KJ, Huiskonen JT, Bowden TA
eLife (2020) 9 [ Pubmed: 33349334 DOI: doi:10.7554/eLife.58242 ]
- Envelope polyprotein (49 kDa, Protein from Puumala orthohantavirus)
- Envelope polyprotein (40 kDa, Protein from Puumala orthohantavirus)
- Puumala orthohantavirus (Virus from Puumala orthohantavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Subtomogram average of Rift Valley fever virus hexamer at pH 5.0 in absence of target membrane
Halldorsson S, Li S, Li M, Harlos K, Bowden TA, Huiskonen JT
Nat Commun (2018) 9 pp. 349-349 [ Pubmed: 29367607 DOI: doi:10.1038/s41467-017-02789-2 ]