Electron Microscopy Data Bank

EMBL

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EMBL-EBI: European Bioinformatics Institute

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primary_citation_author:"Baron GS" AND film_detector_model:"GATAN K3 BIOQUANTUM (6K X 4K)" AND author_name:"Baron GS"

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EMD-28089

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a22L prion fibril

Release date: Nov. 2, 2022
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8efu
Q-score: 0.462

Hoyt F, Alam P, Artikis E, Schwartz CL, Hughson AG, Race B, Baune C, Raymond GJ, Baron GS, Kraus A, Caughey B

PLoS Pathog (2022) 18 pp. e1010947-e1010947 [ Pubmed: 36342968 DOI: doi:10.1371/journal.ppat.1010947 ]

Sample:

Gpi anchorless underglycosylated 22l prion fibril (Complex from Mus musculus)
Major prion protein (25 kDa, Protein from house mouse)

EMD-25824

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aRML prion fibril

Release date: July 20, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7td6
Q-score: 0.501

Hoyt F, Standke HG, Artikis E, Schwartz CL, Hansen B, Li K, Hughson AG, Manca M, Thomas OR, Raymond GJ, Race B, Baron GS, Caughey B, Kraus A

Nat Commun (2022) 13 pp. 4005-4005 [ DOI: doi:10.1038/s41467-022-30458-6 Pubmed: 35831291 ]

Sample:

Major prion protein (28 kDa, Protein from house mouse)
Arml prion (Complex from Mus musculus)

EMD-23459

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Infectious mammalian prion fibril (263K scrapie)

Release date: Sept. 1, 2021
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7lna
Q-score: 0.559

Kraus A, Hoyt F, Schwartz CL, Hansen B, Artikis E, Hughson AG, Raymond GJ, Race B, Baron GS, Caughey B

Mol Cell (2021) 81 pp. 4540- [ DOI: doi:10.1016/j.molcel.2021.08.011 Pubmed: 34433091 ]

Sample:

Major prion protein (16 kDa, Protein from Golden hamster)
Infectious mammalian prion fibril (263k scrapie) (Complex from Mesocricetus auratus)

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