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Neisseria meningitidis Type IV pilus SB-GATDH variant bound to the C24 nanobody
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 8pij
Q-score: 0.558
Fernandez-Martinez D, Kong Y, Goussard S, Zavala A, Gastineau P, Rey M, Ayme G, Chamot-Rooke J, Lafaye P, Vos M, Mechaly A, Dumenil G
Nat Commun (2024) 15 pp. 2414-2414 [ DOI: doi:10.1038/s41467-024-46677-y Pubmed: 38499587 ]
- (2~{r})-~{n}-[(2~{r},3~{s},4~{s},5~{r},6~{r})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide (292 Da, Ligand)
- Sn-glycerol-3-phosphate (172 Da, Ligand)
- Complex of neisseria meningitidis pile sb-gatdh and the c24 nanobody (Complex from Neisseria meningitidis 8013)
- Pilin (17 kDa, Protein from Neisseria meningitidis 8013)
- C24 nanobody (13 kDa, Protein from Vicugna pacos)
Neisseria meningitidis Type IV pilus SB-DATDH variant bound to the C24 nanobody
Resolution: 2.75 Å
EM Method: Helical reconstruction
Fitted PDBs: 8piz
Q-score: 0.547
Fernandez-Martinez D, Kong Y, Goussard S, Zavala A, Gastineau P, Rey M, Ayme G, Chamot-Rooke J, Lafaye P, Vos M, Mechaly A, Dumenil G
Nat Commun (2024) 15 pp. 2414-2414 [ DOI: doi:10.1038/s41467-024-46677-y Pubmed: 38499587 ]
- C24 nanobody (16 kDa, Protein from Vicugna pacos)
- Sn-glycerol-3-phosphate (172 Da, Ligand)
- Pilin (17 kDa, Protein from Neisseria meningitidis 8013)
- Neisseria meningitidis pile, sb-datdh variant, bound to the c24 nanobody (Complex from Neisseria meningitidis 8013)
- 2,4-bisacetamido-2,4,6-trideoxy-beta-d-glucopyranose (246 Da, Ligand)
Neisseria meningitidis PilE, SB-GATDH variant, bound to the F10 nanobody
Resolution: 2.92 Å
EM Method: Helical reconstruction
Fitted PDBs: 8pjp
Q-score: 0.556
Fernandez-Martinez D, Kong Y, Goussard S, Zavala A, Gastineau P, Rey M, Ayme G, Chamot-Rooke J, Lafaye P, Vos M, Mechaly A, Dumenil G
Nat Commun (2024) 15 pp. 2414-2414 [ DOI: doi:10.1038/s41467-024-46677-y Pubmed: 38499587 ]
- (2~{r})-~{n}-[(2~{r},3~{s},4~{s},5~{r},6~{r})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide (292 Da, Ligand)
- Sn-glycerol-3-phosphate (172 Da, Ligand)
- Nanobody f10 (15 kDa, Protein from Vicugna pacos)
- Pilin (17 kDa, Protein from Neisseria meningitidis 8013)
- Neisseria meningitidis pile, variant sa-gatdh complexed with the f10 nanobody (Complex from Neisseria meningitidis 8013)
human alpha7 nicotinic receptor in complex with the C4 nanobody and nicotine
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8cau
Q-score: 0.523
Prevost MS, Barilone N, Dejean de la Batie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ
Nat Commun (2023) 14 pp. 5964-5964 [ Pubmed: 37749098 DOI: doi:10.1038/s41467-023-41734-4 ]
- (s)-3-(1-methylpyrrolidin-2-yl)pyridine (162 Da, Ligand)
- Complex of the human alpha7 nicotinic acetylcholine receptor withthe nanobody c4 and with nicotine (250 kDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nanobody c4 (15 kDa, Protein from Vicugna pacos)
- Human alpha7 nicotinic acetylcholine receptor (Complex from Homo sapiens)
- Nanobody c4 (Complex from Vicugna pacos)
- Neuronal acetylcholine receptor subunit alpha-7 (55 kDa, Protein from Homo sapiens)
Human alpha7 nicotinic receptor in complex with the E3 nanobody
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8ce4
Q-score: 0.6
Prevost MS, Barilone N, Dejean de la Batie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ
Nat Commun (2023) 14 pp. 5964-5964 [ Pubmed: 37749098 DOI: doi:10.1038/s41467-023-41734-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Neuronal acetylcholine receptor subunit alpha-7 (44 kDa, Protein from Homo sapiens)
- Nanobody e3 (15 kDa, Protein from Vicugna pacos)
- Complex of the human alpha7 nicotinic acetylcholine receptor with the nanobody e3 (Complex from Homo sapiens)
- Human alpha7 nicotinic acetylcholine receptor (Complex from Homo sapiens)
- Nanobody e3 (Complex from Vicugna pacos)
Human alpha7 nicotinic receptor in complex with the E3 nanobody and nicotine
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ci1
Q-score: 0.566
Prevost MS, Barilone N, Dejean de la Batie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ
Nat Commun (2023) 14 pp. 5964-5964 [ Pubmed: 37749098 DOI: doi:10.1038/s41467-023-41734-4 ]
- (s)-3-(1-methylpyrrolidin-2-yl)pyridine (162 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Neuronal acetylcholine receptor subunit alpha-7 (44 kDa, Protein from Homo sapiens)
- Complex of the human alpha7 nicotinic acetylcholine receptor with the nanobody e3 (Complex from Homo sapiens)
- Human alpha7 nicotinic acetylcholine receptor (Complex from Homo sapiens)
- Nanobody e3 (Complex from Vicugna pacos)
- Nanobody e3 (15 kDa, Protein from Homo sapiens)
human alpha7 nicotinic receptor in complex with the C4 nanobody under sub-saturating conditions
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 8ci2
Q-score: 0.381
Prevost MS, Barilone N, Dejean de la Batie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ
Nat Commun (2023) 14 pp. 5964-5964 [ Pubmed: 37749098 DOI: doi:10.1038/s41467-023-41734-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Neuronal acetylcholine receptor subunit alpha-7 (44 kDa, Protein from Homo sapiens)
- Nanobody c4 (15 kDa, Protein from Vicugna pacos)
- Complex of the human alpha7 nicotinic acetylcholine receptor with the nanobody c4 and with nicotine (250 kDa, Complex from Homo sapiens)
- Human alpha7 nicotinic acetylcholine receptor (Complex from Homo sapiens)
- Nanobody c4 (Complex from Vicugna pacos)