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Structure of the SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8bon
Q-score: 0.47
Thijssen V, Hurdiss DL, Debski-Antoniak OJ, Spence MA, Franck C, Norman A, Aggarwal A, Mokiem NJ, van Dongen DAA, Vermeir SW, Liu M, Li W, Chatziandreou M, Donselaar T, Du W, Drulyte I, Bosch BJ, Snijder J, Turville SG, Payne RJ, Jackson CJ, van Kuppeveld FJM, Jongkees SAK
PNAS (2023) 120 pp. e2303292120-e2303292120 [ DOI: doi:10.1073/pnas.2303292120 Pubmed: 37339194 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike glycoprotein in complex with the macrocyclic peptide s1b3inl1 (429 kDa, Complex)
- Sars-cov-2 spike glycoprotein (with fibritin tag) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Macrocyclic peptide s1b3inl1 (Complex from Synthetic construct)
- Spike glycoprotein,fibritin (141 kDa, Protein from Tequatrovirus T4)
- Macrocyclic peptide s1b3inl1 (2 kDa, Protein from synthetic construct)
Du W, Janssens R, Mykytyn AZ, Li W, Drabek D, van Haperen R, Chatziandreou M, Rissmann M, van der Lee J, van Dortmondt M, Martin IS, van Kuppeveld FJM, Hurdiss DL, Haagmans BL, Grosveld F, Bosch BJ
Front Immunol (2023) 14 pp. 1111385-1111385 [ DOI: doi:10.3389/fimmu.2023.1111385 Pubmed: 36895554 ]
Du W, Janssens R, Mykytyn AZ, Li W, Drabek D, van Haperen R, Chatziandreou M, Rissmann M, van der Lee J, van Dortmondt M, Martin IS, van Kuppeveld FJM, Hurdiss DL, Haagmans BL, Grosveld F, Bosch BJ
Front Immunol (2023) 14 pp. 1111385-1111385 [ DOI: doi:10.3389/fimmu.2023.1111385 Pubmed: 36895554 ]
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8c8p
Q-score: 0.22
Du W, Janssens R, Mykytyn AZ, Li W, Drabek D, van Haperen R, Chatziandreou M, Rissmann M, van der Lee J, van Dortmondt M, Martin IS, van Kuppeveld FJM, Hurdiss DL, Haagmans BL, Grosveld F, Bosch BJ
Front Immunol (2023) 14 pp. 1111385-1111385 [ DOI: doi:10.3389/fimmu.2023.1111385 Pubmed: 36895554 ]
- Heavy-chain-only antibody 10d12 (41 kDa, Protein from Mus musculus)
- Spike glycoprotein,sars-cov-2 spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike glycoprotein in complex with the 10d12 heavy-chain-only antibody (Complex from Severe acute respiratory syndrome coronavirus 2)