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Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hlp
Q-score: 0.435
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y
Nat Commun (2024) 15 pp. 2772-2772 [ Pubmed: 38555290 DOI: doi:10.1038/s41467-024-47116-8 ]
- Cav3.3 (Complex from Homo sapiens)
- Hexadecane (226 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Homo sapiens)
- Isoform 2c of voltage-dependent l-type calcium channel subunit beta-2 (70 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha (243 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8hma
Q-score: 0.424
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y
Nat Commun (2024) 15 pp. 2772-2772 [ Pubmed: 38555290 DOI: doi:10.1038/s41467-024-47116-8 ]
- Hexadecane (226 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Homo sapiens)
- Isoform 2c of voltage-dependent l-type calcium channel subunit beta-2 (70 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman (620 Da, Ligand)
- Beta-d-mannopyranose (180 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha (243 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Cav1.2alpha2delta1beta2b (Complex from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8hmb
Q-score: 0.472
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y
Nat Commun (2024) 15 pp. 2772-2772 [ Pubmed: 38555290 DOI: doi:10.1038/s41467-024-47116-8 ]
- Cav3.3 (Complex from Homo sapiens)
- Hexadecane (226 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Homo sapiens)
- Isoform 2c of voltage-dependent l-type calcium channel subunit beta-2 (70 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- (3r)-1-benzylpiperidin-3-yl methyl (2r,3r,4r,5r,6s)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate (506 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha (243 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xog
Q-score: 0.294
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Spike glycoprotein,peptide (142 kDa, Protein from synthetic construct)
- Severe acute respiratory syndrome coronavirus (Complex from Severe acute respiratory syndrome coronavirus)
Cryo-EM structure of doubly-bound SNF2h-nucleosome complex (conformation 1)
Chio US, Palovcak E, Smith AAA, Autzen H, Munoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y
Nat Commun (2024) 15 pp. 2225-2225 [ DOI: doi:10.1038/s41467-024-46178-y Pubmed: 38472177 ]
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a member 5 (Protein from Homo sapiens)
- Histone h4 (Protein from Xenopus laevis)
- Widom 601 dna (147-mer) with 60 base pairs flanking dna (reverse strand) (DNA from synthetic construct)
- Widom 601 dna (147-mer) with 60 base pairs flanking dna (forward strand) (DNA from synthetic construct)
- Histone h3.2 (Protein from Xenopus laevis)
- Histone h2a type 1 (Protein from Xenopus laevis)
- Snf2h (100 kDa, Complex from Homo sapiens)
- Atp-dependent chromatin remodeler snf2h in complex with nucleosome (300 kDa, Complex)
- Nucleosome with xenopus laevis histones (200 kDa, Complex)
- Histone h2b 1.1 (Protein from Xenopus laevis)
Cryo-EM structure of doubly-bound SNF2h-nucleosome complex (conformation 2)
Chio US, Palovcak E, Smith AAA, Autzen H, Munoz EN, Yu Z, Wang F, Agard DA, Armache JP, Narlikar GJ, Cheng Y
Nat Commun (2024) 15 pp. 2225-2225 [ DOI: doi:10.1038/s41467-024-46178-y Pubmed: 38472177 ]
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a member 5 (Protein from Homo sapiens)
- Histone h4 (Protein from Xenopus laevis)
- Widom 601 dna (147-mer) with 60 base pairs flanking dna (reverse strand) (DNA from synthetic construct)
- Widom 601 dna (147-mer) with 60 base pairs flanking dna (forward strand) (DNA from synthetic construct)
- Histone h3.2 (Protein from Xenopus laevis)
- Histone h2a type 1 (Protein from Xenopus laevis)
- Snf2h (100 kDa, Complex from Homo sapiens)
- Atp-dependent chromatin remodeler snf2h in complex with nucleosome (300 kDa, Complex)
- Nucleosome with xenopus laevis histones (200 kDa, Complex)
- Histone h2b 1.1 (Protein from Xenopus laevis)
Type IV pilus from Pseudomonas PAO1 strain
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tum
Q-score: 0.448
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L
Science (2024) 384 pp. eadl0635-eadl0635 [ DOI: doi:10.1126/science.adl0635 Pubmed: 38574145 ]
- Type iv major pilin protein pila (14 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Type iv twitching pilus (240 kDa, Cellular component from Pseudomonas aeruginosa)
Asymmetric reconstruction of mature PP7 virions
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L
Science (2024) 384 pp. eadl0635-eadl0635 [ DOI: doi:10.1126/science.adl0635 Pubmed: 38574145 ]
- Type iv twitching pilus (240 kDa, Cellular component from Pseudomonas aeruginosa)
Composite map of PP7 binding to type IV pilus from PAO1
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L
Science (2024) 384 pp. eadl0635-eadl0635 [ DOI: doi:10.1126/science.adl0635 Pubmed: 38574145 ]
- Type iv twitching pilus (240 kDa, Cellular component from Pseudomonas aeruginosa)
Structure of nucleosome-bound SRCAP-C in the apo state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8x15
Q-score: 0.218
Yu J, Sui F, Gu F, Li W, Yu Z, Wang Q, He S, Wang L, Xu Y
Cell Discov (2024) 10 pp. 15-15 [ DOI: doi:10.1038/s41421-023-00640-1 Pubmed: 38331872 ]
- Yeats domain-containing protein 4 (26 kDa, Protein from Homo sapiens)
- Ruvb-like 1 (50 kDa, Protein from Homo sapiens)
- Actin-related protein 6 (45 kDa, Protein from Homo sapiens)
- Structure of nucleosome-bound srcap-c in the apo state (Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Zinc finger hit domain-containing protein 1 (17 kDa, Protein from Homo sapiens)
- Helicase srcap (343 kDa, Protein from Homo sapiens)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Homo sapiens)
- Dna methyltransferase 1-associated protein 1 (53 kDa, Protein from Homo sapiens)
- Dna (137-mer) (41 kDa, DNA from synthetic construct)
- Actin-like protein 6a (47 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Ruvb-like 2 (51 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Vacuolar protein sorting-associated protein 72 homolog (40 kDa, Protein from Homo sapiens)
- Histone h2b type 1-c/e/f/g/i (13 kDa, Protein from Homo sapiens)
- Dna (137-mer) (42 kDa, DNA from synthetic construct)
- Histone h2a type 1-c (14 kDa, Protein from Homo sapiens)