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Cryo-electron microscopy structure of Plasmodium falciparum Rh5/CyRPA/Ripr invasion complex
Resolution: 7.17 Å
EM Method: Single-particle
Fitted PDBs: 6mpv
Q-score: 0.191
Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Sogaard TMM, Jorgensen T, Duraisingh MT, Czabotar PE, de Jongh WA, Tham WH, Webb AI, Yu Z, Cowman AF
Nature (2019) 565 pp. 118-121 [ Pubmed: 30542156 DOI: doi:10.1038/s41586-018-0779-6 ]
- Pfripr (1 kDa, Protein from Plasmodium falciparum 3D7)
- Pfripr (443 Da, Protein from Plasmodium falciparum 3D7)
- Pfrh5/cyrpa/pfripr complex (Complex from Plasmodium falciparum 3D7)
- Cysteine-rich protective antigen (39 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Reticulocyte binding protein 5 (39 kDa, Protein from Plasmodium falciparum)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6duz
Q-score: 0.473
Hu J, Worrall LJ, Hong C, Vuckovic M, Atkinson CE, Caveney N, Yu Z, Strynadka NCJ
Nat Commun (2018) 9 pp. 3840-3840 [ Pubmed: 30242280 DOI: doi:10.1038/s41467-018-06298-8 ]
- Lipoprotein prgk (28 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
- Complex of the periplasmic domains of prgh and prgk from the salmonella spi-1 type iii secretion injectisome needle complex (Complex from Salmonella enterica subsp. enterica serovar Typhimurium)
- Protein prgh (44 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6dv3
Q-score: 0.339
Hu J, Worrall LJ, Hong C, Vuckovic M, Atkinson CE, Caveney N, Yu Z, Strynadka NCJ
Nat Commun (2018) 9 pp. 3840-3840 [ Pubmed: 30242280 DOI: doi:10.1038/s41467-018-06298-8 ]
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6dv6
Q-score: 0.429
Hu J, Worrall LJ, Hong C, Vuckovic M, Atkinson CE, Caveney N, Yu Z, Strynadka NCJ
Nat Commun (2018) 9 pp. 3840-3840 [ Pubmed: 30242280 DOI: doi:10.1038/s41467-018-06298-8 ]
Structure of the Salmonella SPI-1 type III secretion injectisome needle filament
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6dwb
Q-score: 0.484
Hu J, Worrall LJ, Hong C, Vuckovic M, Atkinson CE, Caveney N, Yu Z, Strynadka NCJ
Nat Commun (2018) 9 pp. 3840-3840 [ Pubmed: 30242280 DOI: doi:10.1038/s41467-018-06298-8 ]
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 6d03
Q-score: 0.482
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- Calcium ion (40 Da, Ligand)
- Serotransferrin (77 kDa, Protein from Human)
- Fe (iii) ion (55 Da, Ligand)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from homo sapiens)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 6d04
Q-score: 0.444
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- Calcium ion (40 Da, Ligand)
- Serotransferrin (77 kDa, Protein from Human)
- Fe (iii) ion (55 Da, Ligand)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from Homo sapiens)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6d05
Q-score: 0.419
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- Calcium ion (40 Da, Ligand)
- Serotransferrin (77 kDa, Protein from Human)
- Fe (iii) ion (55 Da, Ligand)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from homo sapiens)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Carbonate ion (60 Da, Ligand)
Integrative Structure and Functional Anatomy of a Nuclear Pore Complex
Kim SJ, Fernandez-Martinez J, Nudelman I, Shi Y, Zhang W, Raveh B, Herricks T, Slaughter BD, Hogan JA, Upla P, Chemmama IE, Pellarin R, Echeverria I, Shivaraju M, Chaudhury AS, Wang J, Williams R, Unruh JR, Greenberg CH, Jacobs EY, Yu Z, de la Cruz MJ, Mironska R, Stokes DL, Aitchison JD, Jarrold MF, Gerton JL, Ludtke SJ, Akey CW, Chait BT, Sali A, Rout MP
Nature (2018) [ Pubmed: 29539637 DOI: doi:10.1038/nature26003 ]
Cryo-EM structure of GATOR1-RAG
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6ces
Q-score: 0.366
Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM
Nature (2018) 556 pp. 64-69 [ DOI: doi:10.1038/nature26158 Pubmed: 29590090 ]
- Gator complex protein nprl3 (63 kDa, Protein from Homo sapiens)
- Gator1-rag (370 kDa, Complex from Homo sapiens)
- Ras-related gtp-binding protein c (44 kDa, Protein from Homo sapiens)
- Gator complex protein depdc5 (181 kDa, Protein from Homo sapiens)
- Gator complex protein nprl2 (43 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Ras-related gtp-binding protein a (36 kDa, Protein from Homo sapiens)