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AP205 phage Acinetobacter gp16 T4P complex
Meng R, Xing Z, Chang JY, Yu Z, Thongchol J, Xiao W, Wang Y, Chamakura K, Zeng Z, Wang F, Young R, Zeng L, Zhang J
Nat Commun (2024) 15 pp. 2746-2746 [ DOI: doi:10.1038/s41467-024-47119-5 Pubmed: 38553443 ]
- Acinetobacter phage ap205 (4 MDa, Virus from Acinetobacter phage AP205)
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6ni2
Q-score: 0.348
Nguyen AH, Thomsen ARB, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ
Nat Struct Mol Biol (2019) 26 pp. 1123-1131 [ DOI: doi:10.1038/s41594-019-0330-y Pubmed: 31740855 ]
- Fab30 (Complex from synthetic construct)
- Stabilized beta-arrestin 1-v2t subcomplex of a gpcr-g protein-beta-arrestin mega-complex (Complex)
- Beta-arrestin-1 (44 kDa, Protein from Bos taurus)
- Fab30 light chain (23 kDa, Protein from synthetic construct)
- Vasopressin 2 tail (Complex from Homo sapiens)
- Beta-arrestin-1 (Complex from Bos taurus)
- Nanobody 32 (13 kDa, Protein from Lama glama)
- Fab30 heavy chain (25 kDa, Protein from synthetic construct)
- Nanobody 32 (Complex from Lama glama)
- Vasopressin v2 receptor (3 kDa, Protein from Homo sapiens)
B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6ni3
Q-score: 0.39
Nguyen AH, Thomsen ARB, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ
Nat Struct Mol Biol (2019) 26 pp. 1123-1131 [ DOI: doi:10.1038/s41594-019-0330-y Pubmed: 31740855 ]
- Endolysin,beta-2 adrenergic receptor chimera (57 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (44 kDa, Protein from Homo sapiens)
- Nanobody 35 (Complex from Lama glama)
- B2v2r-gs protein subcomplex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- 8-[(1r)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2h-1,4-benzoxazin-3(4h)-one (370 Da, Ligand)
- B2v2r-gs protein subcomplex of a gpcr-g protein-beta-arrestin mega-complex (Complex)
- Nanobody 35 (15 kDa, Protein from Lama glama)
Structure of a GPCR-G protein-beta-arrestin mega-complex
Nguyen AH, Thomsen ARB, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ
Nat Struct Mol Biol (2019) 26 pp. 1123-1131 [ DOI: doi:10.1038/s41594-019-0330-y Pubmed: 31740855 ]
Cryo-EM structure of GATOR1-RAG
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6ces
Q-score: 0.366
Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM
Nature (2018) 556 pp. 64-69 [ DOI: doi:10.1038/nature26158 Pubmed: 29590090 ]
- Ras-related gtp-binding protein a (36 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Gator1-rag (370 kDa, Complex from Homo sapiens)
- Ras-related gtp-binding protein c (44 kDa, Protein from Homo sapiens)
- Gator complex protein nprl3 (63 kDa, Protein from Homo sapiens)
- Gator complex protein nprl2 (43 kDa, Protein from Homo sapiens)
- Gator complex protein depdc5 (181 kDa, Protein from Homo sapiens)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6cet
Q-score: 0.318
Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM
Nature (2018) 556 pp. 64-69 [ DOI: doi:10.1038/nature26158 Pubmed: 29590090 ]
- Gator complex protein nprl2 (43 kDa, Protein from Homo sapiens)
- Gator complex protein depdc5 (181 kDa, Protein from Homo sapiens)
- Gator1 (290 kDa, Complex from Homo sapiens)
- Gator complex protein nprl3 (63 kDa, Protein from Homo sapiens)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5tcp
Q-score: 0.418
Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JR, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NC
Nature (2016) 540 pp. 597-601 [ Pubmed: 27974800 DOI: doi:10.1038/nature20576 ]
- Lipoprotein prgk (26 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
- Type iii secretion injectisome basal body (2 MDa, Complex from Salmonella enterica subsp. enterica serovar Typhimurium)
- Protein prgh (30 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5tcq
Q-score: 0.443
Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JR, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NC
Nature (2016) 540 pp. 597-601 [ Pubmed: 27974800 DOI: doi:10.1038/nature20576 ]
6.3 Angstrom structure of the Salmonella SPI-1 type III secretion injectisome basal body
Resolution: 6.3 Å
EM Method: Single-particle
Fitted PDBs: 5tcr
Q-score: 0.179
Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JR, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NC
Nature (2016) 540 pp. 597-601 [ Pubmed: 27974800 DOI: doi:10.1038/nature20576 ]
- Lipoprotein prgk (26 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
- Protein invg (61 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
- Type iii injectisome basal body (2 MDa, Complex from Salmonella enterica subsp. enterica serovar Typhimurium)
- Protein prgh (30 kDa, Protein from Salmonella enterica subsp. enterica serovar Typhimurium)
Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JR, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NC
Nature (2016) 540 pp. 597-601 [ Pubmed: 27974800 DOI: doi:10.1038/nature20576 ]