Cryo-EM structure of ATP13A2 in the E1-ATP state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iek
Q-score: 0.377
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Magnesium ion (24 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the e1-atp state (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cryo-EM structure of ATP13A2 in the E1-like state
Resolution: 5.65 Å
EM Method: Single-particle
Fitted PDBs: 8iel
Q-score: 0.229
Cryo-EM structure of ATP13A2 in the E2P state
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8iem
Q-score: 0.262
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Polyamine-transporting atpase 13a2 (123 kDa, Protein from Homo sapiens)
- Beryllium trifluoride ion (66 Da, Ligand)
- Polyamine-transporting atpase 13a2 (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Spermine (202 Da, Ligand)
Cryo-EM structure of ATP13A2 in the E2-Pi state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8ien
Q-score: -0.047
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Spermine (202 Da, Ligand)
- Cryo-em structure of atp13a2 in the e2-pi state (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the nominal E1P state
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 8ieo
Q-score: 0.312
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Cryo-em structure of atp13a2 in the nominal e1p state (Complex from Homo sapiens)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Spermine (202 Da, Ligand)
Cryo-EM structure of ATP13A2 in the putative of E2 state
Resolution: 4.87 Å
EM Method: Single-particle
Fitted PDBs: 8ier
Q-score: 0.162
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Spermine (202 Da, Ligand)
- Cryo-em structure of atp13a2 in the putative of e2 state (Complex from Homo sapiens)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E1P-ADP state
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8ies
Q-score: 0.308
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Polyamine-transporting atpase 13a2 (125 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the e1p-adp state (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
EM map of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8d4x
Q-score: 0.358
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H
Structure (2023) 31 pp. 541-552.e4 [ Pubmed: 37040767 DOI: doi:10.1016/j.str.2023.03.010 ]
- Homodimer of human e3 ligase ubr5 (610 kDa, Complex from Homo sapiens)
- E3 ubiquitin-protein ligase ubr5 (310 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
EM map of the human UBR5 HECT-type E3 ubiquitin ligase in a C2 symmetric dimeric form
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8e0q
Q-score: 0.425
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H
Structure (2023) 31 pp. 541-552.e4 [ Pubmed: 37040767 DOI: doi:10.1016/j.str.2023.03.010 ]
- Homodimer of human e3 ligase ubr5 (610 kDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- E3 ubiquitin-protein ligase ubr5 (310 kDa, Protein from Homo sapiens)
Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a tetrameric form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8ewi
Q-score: 0.248
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H
Structure (2023) 31 pp. 541-552.e4 [ DOI: doi:10.1016/j.str.2023.03.010 Pubmed: 37040767 ]
- E3 ubiquitin-protein ligase ubr5 (309 kDa, Protein from Homo sapiens)
- Homodimer of human e3 ligase ubr5 (610 kDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)