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Cryo-EM structure of adenosine receptor A3AR bound to CF101
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8x16
Q-score: 0.31
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE
Nat Commun (2024) 15 pp. 3252-3252 [ DOI: doi:10.1038/s41467-024-47207-6 Pubmed: 38627384 ]
- Scfv16 (26 kDa, Protein from Mus musculus)
- Piclidenoson (510 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- G protein (Complex from Rattus norvegicus)
- Adenosine receptor a3 (36 kDa, Protein from Homo sapiens)
- G protein (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Bos taurus)
- Scfv16 (Complex from Mus musculus)
- Cryo-em structure of adenosine receptor a3ar bound to cf101 (160 kDa, Complex)
- A3ar (Complex from Homo sapiens)
Cryo-EM structure of adenosine receptor A3AR bound to CF102
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8x17
Q-score: 0.473
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE
Nat Commun (2024) 15 pp. 3252-3252 [ DOI: doi:10.1038/s41467-024-47207-6 Pubmed: 38627384 ]
- Scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- A3ar (Complex from Rattus norvegicus)
- Cryo-em structure of adenosine receptor a3ar bound to cf102 (160 kDa, Complex)
- Adenosine receptor a3 (36 kDa, Protein from Homo sapiens)
- G protein (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Namodenoson (544 Da, Ligand)
- G protein (Complex from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Bos taurus)
Cryo-EM structure of PfAgo-guide DNA-target DNA complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8jpx
Q-score: 0.575
Wang L, Chen W, Zhang C, Xie X, Huang F, Chen M, Mao W, Yu N, Wei Q, Ma L, Li Z
Mol Cell (2024) 84 pp. 675-686.e4 [ DOI: doi:10.1016/j.molcel.2024.01.004 Pubmed: 38295801 ]
- Excess dna (1 kDa, DNA from Pyrococcus furiosus DSM 3638)
- Magnesium ion (24 Da, Ligand)
- Guide dna (5 kDa, DNA from Pyrococcus furiosus DSM 3638)
- Target dna (5 kDa, DNA from Pyrococcus furiosus DSM 3638)
- Protein argonaute (90 kDa, Protein from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1))
- Cryo-em structure of a pfago-guide dna-target dna complex (Complex from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1))
Cryo-EM structure of TtdAgo-guide DNA-target DNA complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wd8
Q-score: 0.593
Wang L, Chen W, Zhang C, Xie X, Huang F, Chen M, Mao W, Yu N, Wei Q, Ma L, Li Z
Mol Cell (2024) 84 pp. 675-686.e4 [ DOI: doi:10.1016/j.molcel.2024.01.004 Pubmed: 38295801 ]
- Magnesium ion (24 Da, Ligand)
- Argonaute family protein (87 kDa, Protein from Thermococcus thioreducens)
- Dna binding protein (Complex)
- Guide dna (5 kDa, DNA from Thermus thermophilus)
- Target dna (5 kDa, DNA from Thermus thermophilus)
- Dna (Complex)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of ttdago-guide dna-target dna complex (Complex from Thermus thermophilus)
Antibody N3-1 bound to RBDs in the up and down conformations
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8tm1
Q-score: 0.543
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD
Commun Biol (2023) 6 pp. 1250-1250 [ Pubmed: 38082099 DOI: doi:10.1038/s42003-023-05649-6 ]
- N3-1 fab (Complex from Homo sapiens)
- N3-1 fab light chain (11 kDa, Protein from Homo sapiens)
- N3-1 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- The complex of n3-1 fab bound to two receptor binding domains of the spike (Complex)
Antibody N3-1 bound to RBD in the up conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8tma
Q-score: 0.501
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD
Commun Biol (2023) 6 pp. 1250-1250 [ Pubmed: 38082099 DOI: doi:10.1038/s42003-023-05649-6 ]
- N3-1 fab (Complex from Homo sapiens)
- The complex of n3-1 fab bound to one receptor binding domain of the spike (Complex)
- N3-1 fab light chain (11 kDa, Protein from Homo sapiens)
- N3-1 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Antibody N3-1 bound to SARS-CoV-2 spike
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD
Commun Biol (2023) 6 pp. 1250-1250 [ Pubmed: 38082099 DOI: doi:10.1038/s42003-023-05649-6 ]
- Complex of n3-1 bound to sars-cov-2 spike (Complex)
- N3-1 (Complex from Homo sapiens)
- N3-1 fab heavy chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- N3-1 fab light chain (Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8hj1
Q-score: 0.445
Lin X, Chen B, Wu Y, Han Y, Qi A, Wang J, Yang Z, Wei X, Zhao T, Wu L, Xie X, Sun J, Zheng J, Zhao S, Xu F
Nat Commun (2023) 14 pp. 216-216 [ DOI: doi:10.1038/s41467-023-35882-w Pubmed: 36639690 ]
- Gpr21(wt) with gs complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 21 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (16 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (10 kDa, Protein from Homo sapiens)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yve
Q-score: 0.47
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Omicron ba.5 sars-cov-2 s in complex with th027 fab (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Th027 fab light chain (11 kDa, Protein from Homo sapiens)
- Th027 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Th027 fab (Complex from Homo sapiens)
- Omicron ba.4/5 sars-cov-2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH027 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yvf
Q-score: 0.518
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.5 sars-cov-2 s rbd in complex with th027 fab (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Th027 fab light chain (11 kDa, Protein from Homo sapiens)
- Th027 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Th027 fab (Complex from Homo sapiens)