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Cryo-EM structure of adenosine receptor A3AR bound to CF101
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8x16
Q-score: 0.31
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE
Nat Commun (2024) 15 pp. 3252-3252 [ Pubmed: 38627384 DOI: doi:10.1038/s41467-024-47207-6 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- G protein (Complex from Rattus norvegicus)
- Scfv16 (Complex from Mus musculus)
- Piclidenoson (510 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Cryo-em structure of adenosine receptor a3ar bound to cf101 (160 kDa, Complex)
- G protein (Complex from Bos taurus)
- Scfv16 (26 kDa, Protein from Mus musculus)
- A3ar (Complex from Homo sapiens)
- Adenosine receptor a3 (36 kDa, Protein from Homo sapiens)
Cryo-EM structure of adenosine receptor A3AR bound to CF102
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8x17
Q-score: 0.473
Cai H, Guo S, Xu Y, Sun J, Li J, Xia Z, Jiang Y, Xie X, Xu HE
Nat Commun (2024) 15 pp. 3252-3252 [ Pubmed: 38627384 DOI: doi:10.1038/s41467-024-47207-6 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Bos taurus)
- Adenosine receptor a3 (36 kDa, Protein from Homo sapiens)
- G protein (Complex from Homo sapiens)
- Cryo-em structure of adenosine receptor a3ar bound to cf102 (160 kDa, Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- A3ar (Complex from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- G protein (Complex from Bos taurus)
- Scfv16 (26 kDa, Protein from Mus musculus)
- Scfv16 (Complex from Mus musculus)
- Namodenoson (544 Da, Ligand)
Human calcium-sensing receptor bound with cinacalcet in detergent
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8wpg
Q-score: 0.541
Ling S, Meng X, Zhang Y, Xia Z, Zhou Y, Yang F, Shi P, Shi C, Tian C
Cell Res (2024) 34 pp. 169-172 [ Pubmed: 37919470 DOI: doi:10.1038/s41422-023-00892-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- N-[(1r)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine (357 Da, Ligand)
- Tryptophan (204 Da, Ligand)
- Calcium sensing receptor dimer (Complex from Homo sapiens)
- Extracellular calcium-sensing receptor (102 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Human calcium-sensing receptor(CaSR) bound to cinacalcet in complex with Gq protein
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wpu
Q-score: 0.49
Ling S, Meng X, Zhang Y, Xia Z, Zhou Y, Yang F, Shi P, Shi C, Tian C
Cell Res (2024) 34 pp. 169-172 [ Pubmed: 37919470 DOI: doi:10.1038/s41422-023-00892-2 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- N-[(1r)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine (357 Da, Ligand)
- Extracellular calcium-sensing receptor,calcium-sensing receptor (120 kDa, Protein from Homo sapiens)
- Casr-gq complex (Complex from Homo sapiens)
- Tryptophan (204 Da, Ligand)
- G subunit q (gi2-mini-gq chimeric) (28 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Scfv16 (31 kDa, Protein from Rattus norvegicus)
NaVEh Sodium channel, and NaVEh from the coccolithophore Emiliania huxleyi
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7x5v
Q-score: 0.518
Zhang J, Shi Y, Fan J, Chen H, Xia Z, Huang B, Jiang J, Gong J, Huang Z, Jiang D
Nat Commun (2022) 13 pp. 2713-2713 [ Pubmed: 35581266 DOI: doi:10.1038/s41467-022-30400-w ]
- Ion channel,gfp-twinstrep (91 kDa, Protein from Emiliania huxleyi)
- Ion channel (1 kDa, Protein from Emiliania huxleyi)
- Ion channel complex (Complex from Emiliania huxleyi)