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H2 hemagglutinin (A/Singapore/1/1957) in complex with polyclonal Fab, pAb_3
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
BG505 UFO trimer map reconstructed from BG505 UFO-E2p-L4P nanoparticle by localized reconstruction
Wang JYJ, Khmelinskaia A, Sheffler W, Miranda MC, Antanasijevic A, Borst AJ, Torres SV, Shu C, Hsia Y, Nattermann U, Ellis D, Walkey C, Ahlrichs M, Chan S, Kang A, Nguyen H, Sydeman C, Sankaran B, Wu M, Bera AK, Carter L, Fiala B, Murphy M, Baker D, Ward AB, King NP
PNAS (2023) 120 pp. e2214556120-e2214556120 [ Pubmed: 36888664 DOI: doi:10.1073/pnas.2214556120 ]
J08 fragment antigen binding in complex with Omicron SARS-CoV-2-6P S protein
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB
PNAS (2022) 119 pp. e2120976119-e2120976119 [ DOI: doi:10.1073/pnas.2120976119 Pubmed: 35549549 ]
- J08 fragment antigen binding light chain variable domain (Macromolecule from Homo sapiens)
- J08 fragment antigen binding heavy chain variable domain (Macromolecule from Homo sapiens)
- Omicron sars-cov-2-6p s protein (Macromolecule from Severe acute respiratory syndrome coronavirus 2)
- J08 fragment antigen binding in complex with omicron sars-cov-2-6p s protein (Complex from Severe acute respiratory syndrome coronavirus 2)
Structure of OC43 spike in complex with polyclonal Fab9 (Donor 1412)
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 and EBOV-515
Resolution: 6.6 Å
EM Method: Single-particle
Fitted PDBs: 7kfe
Q-score: 0.171
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep (2021) 35 pp. 108984-108984 [ Pubmed: 33852862 DOI: doi:10.1016/j.celrep.2021.108984 ]
- Bundibugyo virus gp (mucin deleted) (Complex from Bundibugyo ebolavirus)
- Antibody bdbv-329 light chain (23 kDa, Protein from Homo sapiens)
- Antibody fab bdbv-329 (Complex from Homo sapiens)
- Spike glycoprotein 1 (38 kDa, Protein from Bundibugyo ebolavirus)
- Envelope glycoprotein 2 (19 kDa, Protein from Bundibugyo ebolavirus)
- Bundibugyo virus gp (mucin deleted) bound to antibody fab ebov-329 and ebov-515 (Complex from Bundibugyo ebolavirus)
- Antibody bdbv-329 heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
BG505 SOSIPv5.2 in complex with PGT122 and three RM20E1 Fabs
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ DOI: doi:10.1016/j.celrep.2021.108933 Pubmed: 33826885 ]
BG505 SOSIPv5.2 in complex with PGT122 and one RM20E1 Fab
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee WH, Aldon Y, Rantalainen K, Antanasijevic A, Copps J, Yasmeen A, Cupo A, Cruz Portillo VM, Poniman M, Bol N, van der Woude P, de Taeye SW, van den Kerkhof TLGM, Klasse PJ, Ozorowski G, van Gils MJ, Moore JP, Ward AB, Crispin M, Sanders RW
Cell Rep (2021) 35 pp. 108933-108933 [ DOI: doi:10.1016/j.celrep.2021.108933 Pubmed: 33826885 ]