PhK holoenzyme in inactive state, muscle isoform
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8jfk
Q-score: 0.265
Yang X, Zhu M, Lu X, Wang Y, Xiao J
Nat Commun (2024) 15 pp. 2719-2719 [ Pubmed: 38548794 DOI: doi:10.1038/s41467-024-47049-2 ]
- Phosphorylase b kinase, muscle isoform (Complex from Homo sapiens)
- Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (137 kDa, Protein from Homo sapiens)
- Phosphorylase b kinase regulatory subunit beta (125 kDa, Protein from Homo sapiens)
- Farnesyl (206 Da, Ligand)
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (45 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
PhK holoenzyme in active state, muscle isoform
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8jfl
Q-score: 0.396
Yang X, Zhu M, Lu X, Wang Y, Xiao J
Nat Commun (2024) 15 pp. 2719-2719 [ Pubmed: 38548794 DOI: doi:10.1038/s41467-024-47049-2 ]
- Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (137 kDa, Protein from Homo sapiens)
- Phosphorylase b kinase, muscle isoform, ca2+ active state (Complex from Homo sapiens)
- Phosphorylase b kinase regulatory subunit beta (125 kDa, Protein from Homo sapiens)
- Farnesyl (206 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (45 kDa, Protein from Homo sapiens)
local map of hPhK alpha-beta-gamma-delta subcomplex in inactive state
Cryo-EM structure of human FcmR bound to sIgM
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 7ysg
Q-score: 0.417
Li Y, Shen H, Zhang R, Ji C, Wang Y, Su C, Xiao J
Nature (2023) 615 pp. 907-912 [ Pubmed: 36949194 DOI: doi:10.1038/s41586-023-05835-w ]
- Immunoglobulin heavy constant mu (Complex from Homo sapiens)
- Immunoglobulin j chain (Complex from Homo sapiens)
- Fas apoptotic inhibitory molecule 3 (11 kDa, Protein from Homo sapiens)
- Fas apoptotic inhibitory molecule 3 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Secretory component (Complex from Homo sapiens)
- Secretory component (59 kDa, Protein from Homo sapiens)
- Cryo-em structure of human fcmr bound to sigm (Complex from Homo sapiens)
- Immunoglobulin heavy constant mu (25 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
Cryo-EM structure of human FcmR bound to IgM-Fc/J
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 7ytc
Q-score: 0.367
Li Y, Shen H, Zhang R, Ji C, Wang Y, Su C, Xiao J
Nature (2023) 615 pp. 907-912 [ Pubmed: 36949194 DOI: doi:10.1038/s41586-023-05835-w ]
- Immunoglobulin heavy constant mu (Complex from Homo sapiens)
- Immunoglobulin j chain (Complex from Homo sapiens)
- Fas apoptotic inhibitory molecule 3 (11 kDa, Protein from Homo sapiens)
- Fcmr (Complex)
- Cryo-em structure of human fcmr bound to igm-fc/j (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (25 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
Cryo-EM structure of four human FcmR bound to IgM-Fc/J
Resolution: 3.71 Å
EM Method: Single-particle
Fitted PDBs: 7ytd
Q-score: 0.317
Li Y, Shen H, Zhang R, Ji C, Wang Y, Su C, Xiao J
Nature (2023) 615 pp. 907-912 [ Pubmed: 36949194 DOI: doi:10.1038/s41586-023-05835-w ]
- Immunoglobulin heavy constant mu (Complex from Homo sapiens)
- Cryo-em structure of four human fcmr bound to igm-fc/j (Complex from Homo sapiens)
- Immunoglobulin j chain (Complex from Homo sapiens)
- Fas apoptotic inhibitory molecule 3 (11 kDa, Protein from Homo sapiens)
- Fcmr (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant mu (25 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (15 kDa, Protein from Homo sapiens)
Cryo-EM structure of human secretory immunoglobulin A
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 6lx3
Q-score: 0.545
Wang Y, Wang G, Li Y, Zhu Q, Shen H, Gao N, Xiao J
Cell Res (2020) 30 pp. 602-609 [ DOI: doi:10.1038/s41422-020-0336-3 Pubmed: 32398862 ]
- Immunoglobulin j chain (19 kDa, Protein from Homo sapiens)
- Interleukin-2,immunoglobulin heavy constant alpha 1 (31 kDa, Protein from Homo sapiens)
- Ternary complex of iga-fc with the j chain and pigr/sc (Complex from Homo sapiens)
- Polymeric immunoglobulin receptor (63 kDa, Protein from Homo sapiens)
Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 6lxw
Q-score: 0.513
Wang Y, Wang G, Li Y, Zhu Q, Shen H, Gao N, Xiao J
Cell Res (2020) 30 pp. 602-609 [ DOI: doi:10.1038/s41422-020-0336-3 Pubmed: 32398862 ]
- Interleukin-2,immunoglobulin heavy constant alpha 1 (31 kDa, Protein from Homo sapiens)
- Immunoglobulin j chain (19 kDa, Protein from Homo sapiens)
- Siga binding protein (36 kDa, Protein from Streptococcus pneumoniae)
- Quadruple complex of human secretory immunoglobulin a with the n-terminal domain of spsa (Complex from Homo sapiens)
- Polymeric immunoglobulin receptor (63 kDa, Protein from Homo sapiens)