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Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hlp
Q-score: 0.435
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y
Nat Commun (2024) 15 pp. 2772-2772 [ DOI: doi:10.1038/s41467-024-47116-8 Pubmed: 38555290 ]
- Voltage-dependent l-type calcium channel subunit alpha (243 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Isoform 2c of voltage-dependent l-type calcium channel subunit beta-2 (70 kDa, Protein from Homo sapiens)
- Cav3.3 (Complex from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Homo sapiens)
- Hexadecane (226 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8hma
Q-score: 0.424
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y
Nat Commun (2024) 15 pp. 2772-2772 [ DOI: doi:10.1038/s41467-024-47116-8 Pubmed: 38555290 ]
- Beta-d-mannopyranose (180 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha (243 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Isoform 2c of voltage-dependent l-type calcium channel subunit beta-2 (70 kDa, Protein from Homo sapiens)
- Cav1.2alpha2delta1beta2b (Complex from Homo sapiens)
- 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman (620 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Homo sapiens)
- Hexadecane (226 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8hmb
Q-score: 0.472
Wei Y, Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y, Xu H, Wang X, Dong Y, Huang Z, Zhang XC, Zhao Y
Nat Commun (2024) 15 pp. 2772-2772 [ DOI: doi:10.1038/s41467-024-47116-8 Pubmed: 38555290 ]
- Voltage-dependent l-type calcium channel subunit alpha (243 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Isoform 2c of voltage-dependent l-type calcium channel subunit beta-2 (70 kDa, Protein from Homo sapiens)
- Cav3.3 (Complex from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Homo sapiens)
- (3r)-1-benzylpiperidin-3-yl methyl (2r,3r,4r,5r,6s)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate (506 Da, Ligand)
- Hexadecane (226 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the prokaryotic SPARSA system complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8jkz
Q-score: 0.475
Zhen X, Xu X, Ye L, Xie S, Huang Z, Yang S, Wang Y, Li J, Long F, Ouyang S
Nat Commun (2024) 15 pp. 450-450 [ Pubmed: 38200015 DOI: doi:10.1038/s41467-023-44660-7 ]
- Sir2/ago (Complex from Geobacter sulfurreducens PCA)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Piwi domain protein (53 kDa, Protein from Geobacter sulfurreducens)
- Sir2 superfamily protein (66 kDa, Protein from Geobacter sulfurreducens)
- Sir2 (Complex from Geobacter sulfurreducens PCA)
- Ago (Complex)
Cryo-EM structure of the prokaryotic SPARSA system complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8jl0
Q-score: 0.547
Zhen X, Xu X, Ye L, Xie S, Huang Z, Yang S, Wang Y, Li J, Long F, Ouyang S
Nat Commun (2024) 15 pp. 450-450 [ Pubmed: 38200015 DOI: doi:10.1038/s41467-023-44660-7 ]
- Dna (5'-d(p*ap*cp*gp*ap*cp*gp*tp*cp*tp*ap*ap*gp*ap*ap*ap*cp*cp*ap*tp*tp*ap*t)-3') (6 kDa, DNA from synthetic construct)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Piwi domain protein (53 kDa, Protein from Geobacter sulfurreducens)
- Sir2 superfamily protein (66 kDa, Protein from Geobacter sulfurreducens)
- The sir2/ago/guide rna/recognition dna complex (Complex from Geobacter sulfurreducens PCA)
- Sir2 (Complex from Geobacter sulfurreducens PCA)
- Dna/guide rna duplex (Complex)
- Rna (5'-r(p*ap*up*ap*ap*up*gp*gp*up*up*up*cp*up*up*ap*gp*ap*cp*gp*up*cp*gp*u)-3') (6 kDa, RNA from synthetic construct)
- Ago (Complex)
Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7ysw
Q-score: 0.482
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ DOI: doi:10.1038/s41586-023-06155-9 Pubmed: 37286607 ]
- Fgf23 (Complex)
- Copper (ii) ion (63 Da, Ligand)
- Klotho (108 kDa, Protein from Homo sapiens)
- Fibroblast growth factor 23 (20 kDa, Protein from Homo sapiens)
- Fibroblast growth factor receptor 4 (23 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Fgfr4-aklotho-hs (Complex)
- 1:2:1:1 fgf23-fgfr4-aklotho-hs quaternary complex (Complex from Homo sapiens)
Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7ysh
Q-score: 0.555
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ DOI: doi:10.1038/s41586-023-06155-9 Pubmed: 37286607 ]
- Copper (ii) ion (63 Da, Ligand)
- 1:2:1:1 fgf23-fgfr1c-aklotho-hs quaternary complex (Complex from Homo sapiens)
- Fibroblast growth factor 23 (30 kDa, Protein from Homo sapiens)
- Klotho (109 kDa, Protein from Homo sapiens)
- Isoform 20 of fibroblast growth factor receptor 1 (26 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ysu
Q-score: 0.479
Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, Liang G, Li X, Chen G, Mohammadi M
Nature (2023) 618 pp. 862-870 [ DOI: doi:10.1038/s41586-023-06155-9 Pubmed: 37286607 ]
- Copper (ii) ion (63 Da, Ligand)
- Aklotho,fgfr3 (Complex from Homo sapiens)
- Fgf23 (Complex from Homo sapiens)
- Klotho (108 kDa, Protein from Homo sapiens)
- Fibroblast growth factor 23 (20 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 1:2:1:1 fgf23-fgfr3c-aklotho-hs quaternary complex (Complex)
- Fibroblast growth factor receptor 3 (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of expanded coxsackievirus A16 empty particle after incubation with 8C4 antibody
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7yv2
Q-score: 0.464
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ Pubmed: 36543790 DOI: doi:10.1038/s41467-022-35575-w ]
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of expanded coxsackievirus a16 empty particle after incubation with 8c4 antibody (Complex from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of expanded coxsackievirus A16 empty particle in complex with antibody 9B5
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yv7
Q-score: 0.274
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z
Nat Commun (2022) 13 pp. 7854-7854 [ Pubmed: 36543790 DOI: doi:10.1038/s41467-022-35575-w ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Cryo-em structure of expanded coxsackievirus a16 empty particle in complex with antibody 9b5 (Complex from Coxsackievirus A16)
- The light chain of antibody 9b5 (23 kDa, Protein from Coxsackievirus A16)
- The heavy chain of antibody 9b5 (23 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)