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The structure of EBOV L-VP35-RNA complex
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8jsl
Q-score: 0.547
Peng Q, Yuan B, Cheng J, Wang M, Gao S, Bai S, Zhao X, Qi J, Gao GF, Shi Y
Nature (2023) 622 pp. 603-610 [ Pubmed: 37699521 DOI: doi:10.1038/s41586-023-06608-1 ]
- The leader sequence of ebov (5 kDa, RNA from Ebola virus)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (252 kDa, Protein from Ebola virus)
- Polymerase cofactor vp35 (37 kDa, Protein from Ebola virus)
- The structure of ebov l-vp35-rna complex (Complex from Ebola virus)
The structure of EBOV L-VP35-RNA complex (conformation 1)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8jsm
Q-score: 0.495
Peng Q, Yuan B, Cheng J, Wang M, Gao S, Bai S, Zhao X, Qi J, Gao GF, Shi Y
Nature (2023) 622 pp. 603-610 [ Pubmed: 37699521 DOI: doi:10.1038/s41586-023-06608-1 ]
- The leader sequence of ebov genome. (5 kDa, RNA from Ebola virus)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (252 kDa, Protein from Ebola virus)
- Polymerase cofactor vp35 (37 kDa, Protein from Ebola virus)
- The structure of ebov l-vp35-rna complex (conformation 1) (Complex from Ebola virus)
The structure of EBOV L-VP35-RNA complex (conformation 2)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8jsn
Q-score: 0.475
Peng Q, Yuan B, Cheng J, Wang M, Gao S, Bai S, Zhao X, Qi J, Gao GF, Shi Y
Nature (2023) 622 pp. 603-610 [ Pubmed: 37699521 DOI: doi:10.1038/s41586-023-06608-1 ]
- The leader sequence of ebov genome (5 kDa, RNA from Ebola virus)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (252 kDa, Protein from Ebola virus)
- The structure of ebov l-vp35-rna complex (conformation 2) (Complex from Ebola virus)
- Polymerase cofactor vp35 (37 kDa, Protein from Ebola virus)
The structure of EBOV L-VP35 complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7yer
Q-score: 0.531
Yuan B, Peng Q, Cheng J, Wang M, Zhong J, Qi J, Gao GF, Shi Y
Nature (2022) 610 pp. 394-401 [ Pubmed: 36171293 DOI: doi:10.1038/s41586-022-05271-2 ]
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (252 kDa, Protein from Ebola virus)
- The complex of ebov l-vp35 (Complex from Ebola virus)
- Polymerase cofactor vp35 (37 kDa, Protein from Ebola virus)
The structure of EBOV L-VP35-RNA complex (state2)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yes
Q-score: 0.49
Yuan B, Peng Q, Cheng J, Wang M, Zhong J, Qi J, Gao GF, Shi Y
Nature (2022) 610 pp. 394-401 [ Pubmed: 36171293 DOI: doi:10.1038/s41586-022-05271-2 ]
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (252 kDa, Protein from Ebola virus)
- The complex of ebov l-vp35 (Complex from Ebola virus)
- Vp35 of ebov l-vp35 complex (37 kDa, Protein from Ebola virus)
The structure of EBOV L-VP35 in complex with suramin
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7yet
Q-score: 0.45
Yuan B, Peng Q, Cheng J, Wang M, Zhong J, Qi J, Gao GF, Shi Y
Nature (2022) 610 pp. 394-401 [ Pubmed: 36171293 DOI: doi:10.1038/s41586-022-05271-2 ]
- The complex of ebov l-vp35-suramin (Complex from Ebola virus)
- Rna-directed rna polymerase l (252 kDa, Protein from Ebola virus)
- 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfon ic acid (1 kDa, Ligand)
- Polymerase cofactor vp35 (37 kDa, Protein from Ebola virus)