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Resolution: 3.83 Å
EM Method: Single-particle
Fitted PDBs: 7t6x
Q-score: 0.381
Torrents de la Pena A, Sliepen K, Eshun-Wilson L, Newby ML, Allen JD, Zon I, Koekkoek S, Chumbe A, Crispin M, Schinkel J, Lander GC, Sanders RW, Ward AB
Science (2022) 378 pp. 263-269 [ Pubmed: 36264808 DOI: doi:10.1126/science.abn9884 ]
- Ar4a fab, heavy chain (29 kDa, Protein from Homo sapiens)
- Cryoem structure of full-length hepatitis c virus e1e2 glycoprotein in complex with ar4a, at12009 and igh505 fabs (Complex from Hepacivirus C)
- Igh505, lambda light chain (24 kDa, Protein from Homo sapiens)
- Envelope glycoprotein e2 (40 kDa, Protein from Hepacivirus C)
- Igh505, heavy chain (52 kDa, Protein from Homo sapiens)
- At12009 crossmab, light kappa chain (24 kDa, Protein from Homo sapiens)
- At12009 crossmab, heavy chain (29 kDa, Protein from Homo sapiens)
- Ar4a, kappa light chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein e1 (20 kDa, Protein from Hepacivirus C)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124
Resolution: 3.99 Å
EM Method: Single-particle
Fitted PDBs: 7zlk
Q-score: 0.362
van Schooten J, Schorcht A, Farokhi E, Umotoy JC, Gao H, van den Kerkhof TLGM, Dorning J, Rijkhold Meesters TG, van der Woude P, Burger JA, Bijl T, Ghalaiyini R, Torrents de la Pena A, Turner HL, Labranche CC, Stanfield RL, Sok D, Schuitemaker H, Montefiori DC, Burton DR, Ozorowski G, Seaman MS, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2022) 18 pp. e1010945-e1010945 [ Pubmed: 36395347 DOI: doi:10.1371/journal.ppat.1010945 ]
- Amc009 sosipv5.2 in complex with fabs acs114 and acs122 (17 MDa, Complex from Human immunodeficiency virus 1)
- Acs114 light chain (12 kDa, Protein from Homo sapiens)
- Acs122 heavy chain (13 kDa, Protein from Homo sapiens)
- Acs122 light chain (11 kDa, Protein from Homo sapiens)
- Amc009 sosipv5.2 envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Amc009 sosipv5.2 envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Acs114 heavy chain (13 kDa, Protein from Homo sapiens)
AMC009 SOSIP.v4.2 in complex with PGV04 Fab
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 6vo3
Q-score: 0.29
Schorcht A, van den Kerkhof TLGM, Cottrell CA, Allen JD, Torres JL, Behrens AJ, Schermer EE, Burger JA, de Taeye SW, Torrents de la Pena A, Bontjer I, Gumbs S, Ozorowski G, LaBranche CC, de Val N, Yasmeen A, Klasse PJ, Montefiori DC, Moore JP, Schuitemaker H, Crispin M, van Gils MJ, Ward AB, Sanders RW
J Virol (2020) 94 [ DOI: doi:10.1128/JVI.01214-20 Pubmed: 32999024 ]
- Amc009 sosip.v4.2 envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Pgv04 light chain (23 kDa, Protein from Homo sapiens)
- Amc009 sosip.v4.2 envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgv04 fab (Complex from Homo sapiens)
- Amc009 sosip.v4.2 in complex with pgv04 fab (Complex)
- Amc009 sosip.v4.2 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pgv04 heavy chain (24 kDa, Protein from Homo sapiens)
PGT145 Fab in complex with full length AMC011 HIV-1 Env
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 6nij
Q-score: 0.18
Torrents de la Pena A, Rantalainen K, Cottrell CA, Allen JD, van Gils MJ, Torres JL, Crispin M, Sanders RW, Ward AB
PLoS Pathog (2019) 15 pp. e1007920-e1007920 [ Pubmed: 31306470 DOI: doi:10.1371/journal.ppat.1007920 ]
- Amc011 glycoprotein 120 (Complex from Homo sapiens)
- Amc011 glycoprotein 41 (39 kDa, Protein from Human immunodeficiency virus 1)
- Pgt145 fab light chain (12 kDa, Protein from Homo sapiens)
- Pgt145 (Complex from Homo sapiens)
- Amc011 glycoprotein 120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Pgt145 fab in complex with full length amc011 hiv-1 env (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pgt145 fab heavy chain (15 kDa, Protein from Homo sapiens)
- Amc011 glycoprotein 41 (Complex from Homo sapiens)