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Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7zgp
Q-score: 0.624
Rodriguez-Molina JB, O'Reilly FJ, Fagarasan H, Sheekey E, Maslen S, Skehel JM, Rappsilber J, Passmore LA
Mol Cell (2022) 82 pp. 2490- [ DOI: doi:10.1016/j.molcel.2022.04.021 Pubmed: 35584695 ]
- Mrna 3'-end-processing protein yth1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Protein cft1 (153 kDa, Protein from Saccharomyces cerevisiae)
- Pre-cleaved cyc1 (13 kDa, RNA from Saccharomyces cerevisiae)
- Polymerase module-mpe1-rna (Complex from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Polyadenylation factor subunit 2 (53 kDa, Protein from Saccharomyces cerevisiae)
- Mpe1 isoform 1 (49 kDa, Protein from Saccharomyces cerevisiae)
Polymerase module of yeast CPF in complex with the yPIM of Cft2
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7zgq
Q-score: 0.582
Rodriguez-Molina JB, O'Reilly FJ, Fagarasan H, Sheekey E, Maslen S, Skehel JM, Rappsilber J, Passmore LA
Mol Cell (2022) 82 pp. 2490- [ DOI: doi:10.1016/j.molcel.2022.04.021 Pubmed: 35584695 ]
- Mrna 3'-end-processing protein yth1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Protein cft1 (153 kDa, Protein from Saccharomyces cerevisiae)
- Polymerase module-mpe1-cft2(s)-rna (Complex from Saccharomyces cerevisiae)
- Cleavage factor two protein 2 (80 kDa, Protein from Saccharomyces cerevisiae)
- Polyadenylation factor subunit 2 (53 kDa, Protein from Saccharomyces cerevisiae)
Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7zgr
Q-score: 0.61
Rodriguez-Molina JB, O'Reilly FJ, Fagarasan H, Sheekey E, Maslen S, Skehel JM, Rappsilber J, Passmore LA
Mol Cell (2022) 82 pp. 2490- [ DOI: doi:10.1016/j.molcel.2022.04.021 Pubmed: 35584695 ]
- Mrna 3'-end-processing protein yth1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Protein cft1 (153 kDa, Protein from Saccharomyces cerevisiae)
- Pre-cleaved cyc1 (13 kDa, RNA from Saccharomyces cerevisiae)
- Cleavage factor two protein 2 (80 kDa, Protein from Saccharomyces cerevisiae)
- Polymerase module-mpe1-ypim-rna (Complex from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Polyadenylation factor subunit 2 (53 kDa, Protein from Saccharomyces cerevisiae)
- Mpe1 isoform 1 (49 kDa, Protein from Saccharomyces cerevisiae)
Structure of Fanconi anaemia core complex (consensus map)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6sri
Q-score: 0.112
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ Pubmed: 31666700 DOI: doi:10.1038/s41586-019-1703-4 ]
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (5 kDa, Protein from Gallus gallus)
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (3 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100: chain f,f; base region, proposed fancc-fanc-e-fancf: chain z) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (783 Da, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (10 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (6 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (3 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100: chain a,a; base region, proposed fancc-fanc-e-fancf: chain 3) (6 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Base region, proposed fancf (17 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (top region, proposed fancg) (12 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (9 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (19 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (top region, proposed fancg) (24 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (2 kDa, Protein from Gallus gallus)
- Fanconi anaemia protein fancl (42 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (7 kDa, Protein from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for top region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ Pubmed: 31666700 DOI: doi:10.1038/s41586-019-1703-4 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for middle region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ Pubmed: 31666700 DOI: doi:10.1038/s41586-019-1703-4 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for base region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ Pubmed: 31666700 DOI: doi:10.1038/s41586-019-1703-4 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi anaemia core subcomplex
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6srs
Q-score: 0.135
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ Pubmed: 31666700 DOI: doi:10.1038/s41586-019-1703-4 ]
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (3 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (783 Da, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (10 kDa, Protein from Gallus gallus)
- Fanconi anaemia protein fancl (10 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Fanconi anaemia core subcomplex (860 kDa, Complex from Gallus gallus)
- Unassigned secondary structure elements (proposed fancg) (24 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (3 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancg) (12 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (6 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (23 kDa, Protein from Gallus gallus)