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human glycine transporter 1 in complex with glycine in occluded conformation
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 8wfi
Q-score: 0.644
Wei Y, Li R, Meng Y, Hu T, Zhao J, Gao Y, Bai Q, Li N, Zhao Y
Cell (2024) 187 pp. 1719- [ Pubmed: 38513663 DOI: doi:10.1016/j.cell.2024.02.026 ]
- Glycine (75 Da, Ligand)
- Isoform glyt-1b of sodium- and chloride-dependent glycine transporter 1 (63 kDa, Protein from Homo sapiens)
- Human glycine transporter 1 (glyt1) (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Sodium ion (22 Da, Ligand)
human glycine transporter 1 in complex with ALX-5407 in inward facing conformation
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8wfj
Q-score: 0.479
Wei Y, Li R, Meng Y, Hu T, Zhao J, Gao Y, Bai Q, Li N, Zhao Y
Cell (2024) 187 pp. 1719- [ Pubmed: 38513663 DOI: doi:10.1016/j.cell.2024.02.026 ]
- Sodium- and chloride-dependent glycine transporter 1 (72 kDa, Protein from Homo sapiens)
- Human glycine transporter 1 (Complex from Homo sapiens)
- Alx5407 (393 Da, Ligand)
human glycine transporter 1 in complex with SSR504734 in outward facing conformation
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8wfk
Q-score: 0.542
Wei Y, Li R, Meng Y, Hu T, Zhao J, Gao Y, Bai Q, Li N, Zhao Y
Cell (2024) 187 pp. 1719- [ Pubmed: 38513663 DOI: doi:10.1016/j.cell.2024.02.026 ]
- Ssr504734 (396 Da, Ligand)
- Sodium- and chloride-dependent glycine transporter 1 (72 kDa, Protein from Homo sapiens)
- Human glycine transporter 1 (Complex from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Sodium ion (22 Da, Ligand)
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8wfl
Q-score: 0.47
Wei Y, Li R, Meng Y, Hu T, Zhao J, Gao Y, Bai Q, Li N, Zhao Y
Cell (2024) 187 pp. 1719- [ Pubmed: 38513663 DOI: doi:10.1016/j.cell.2024.02.026 ]
- Pf-3463275 (376 Da, Ligand)
- Sodium- and chloride-dependent glycine transporter 1 (72 kDa, Protein from Homo sapiens)
- Human glycine transporter 1 (Complex from Homo sapiens)
Human VMAT2 complex with serotonin
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8jsw
Q-score: 0.578
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ DOI: doi:10.1038/s41586-023-06926-4 Pubmed: 38081299 ]
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Transportera (Complex from Homo sapiens)
Human VMAT2 complex with tetrabenazine
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8jta
Q-score: 0.506
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ DOI: doi:10.1038/s41586-023-06926-4 Pubmed: 38081299 ]
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Transporter2 (Complex from Homo sapiens)
- Tetrabenazine (317 Da, Ligand)
Human VMAT2 complex with reserpine
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8jtc
Q-score: 0.481
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ DOI: doi:10.1038/s41586-023-06926-4 Pubmed: 38081299 ]
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Reserpine (608 Da, Ligand)
- Transportera (Complex from Homo sapiens)
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 6k61
Q-score: 0.65
Zheng L, Li Y, Li X, Zhong Q, Li N, Zhang K, Zhang Y, Chu H, Ma C, Li G, Zhao J, Gao N
Nat Plants (2019) 5 pp. 1087-1097 [ Pubmed: 31595062 DOI: doi:10.1038/s41477-019-0525-6 ]
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i reaction center subunit xii (3 kDa, Protein from Nostoc sp. PCC 7120)
- Chlorophyll a (893 Da, Ligand)
- Photosystem i iron-sulfur center (8 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i reaction center subunit ix (5 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i reaction center subunit iii (17 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i 4.8 kda protein (4 kDa, Protein from Nostoc sp. PCC 7120)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Photosystem i complex of cyanobacterium anabaena sp. pcc 7120 (1 MDa, Cellular component from Nostoc sp. PCC 7120)
- Photosystem i p700 chlorophyll a apoprotein a2 1 (83 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i reaction center subunit xi (18 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i reaction center subunit viii (5 kDa, Protein from Nostoc sp. PCC 7120)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- Chlorophyll a isomer (893 Da, Ligand)
- Photosystem i reaction center subunit ii (15 kDa, Protein from Nostoc sp. PCC 7120)
- Photosystem i reaction center subunit psak 1 (8 kDa, Protein from Nostoc sp. PCC 7120)
- Iron/sulfur cluster (351 Da, Ligand)
- Photosystem i reaction center subunit iv (7 kDa, Protein from Nostoc sp. PCC 7120)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Beta-carotene (536 Da, Ligand)
- Phylloquinone (450 Da, Ligand)