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CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7sfu
Q-score: 0.332
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS
J Exp Med (2022) 219 [ DOI: doi:10.1084/jem.20212532 Pubmed: 35297953 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Capsid protein (18 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e2 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7sfv
Q-score: 0.324
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS
J Exp Med (2022) 219 [ DOI: doi:10.1084/jem.20212532 Pubmed: 35297953 ]
- Hveev-63 fab light chain (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Hveev-63 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Capsid protein (17 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e2 (46 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7sfw
Q-score: 0.508
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS
J Exp Med (2022) 219 [ DOI: doi:10.1084/jem.20212532 Pubmed: 35297953 ]
- Capsid protein (30 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hveev-63 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Venezuelan equine encephalitis virus (strain tc-83) (Virus from Venezuelan equine encephalitis virus (strain TC-83))
- Spike glycoprotein e2 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
- Hveev-63 fab light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein e1 (47 kDa, Protein from Venezuelan equine encephalitis virus (strain TC-83))
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-143 Antibody
Williamson LE, Gilliland Jr T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe Jr JE
Cell (2020) 183 pp. 1884-1900.e23 [ DOI: doi:10.1016/j.cell.2020.11.011 Pubmed: 33301709 ]
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-33 Antibody
Williamson LE, Gilliland Jr T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe Jr JE
Cell (2020) 183 pp. 1884-1900.e23 [ DOI: doi:10.1016/j.cell.2020.11.011 Pubmed: 33301709 ]
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6xo4
Q-score: 0.343
Williamson LE, Gilliland Jr T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe Jr JE
Cell (2020) 183 pp. 1884-1900.e23 [ DOI: doi:10.1016/j.cell.2020.11.011 Pubmed: 33301709 ]
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Togavirin (47 kDa, Protein from Eastern equine encephalitis virus)
- Togavirin (47 kDa, Protein from Eastern equine encephalitis virus)
- Togavirin (29 kDa, Protein from Eastern equine encephalitis virus)
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
Resolution: 8.5 Å
EM Method: Single-particle
Fitted PDBs: 6xob
Q-score: 0.182
Williamson LE, Gilliland Jr T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe Jr JE
Cell (2020) 183 pp. 1884-1900.e23 [ DOI: doi:10.1016/j.cell.2020.11.011 Pubmed: 33301709 ]
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- Eeev-143 fab light chain (23 kDa, Protein from Homo sapiens)
- Eeev-143 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Togavirin (29 kDa, Protein from Eastern equine encephalitis virus)
- Togavirin (47 kDa, Protein from Eastern equine encephalitis virus)
- Togavirin (47 kDa, Protein from Eastern equine encephalitis virus)
Resolution: 6.33 Å
EM Method: Single-particle
Fitted PDBs: 6vyv
Q-score: 0.339
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Ross river virus (strain t48) (Virus from Ross river virus (strain T48))
- E1 glycoprotein (42 kDa, Protein from Ross river virus (strain T48))
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Ross river virus (strain T48))
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w09
Q-score: 0.34
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (42 kDa, Protein from Chikungunya virus)
- Chikungunya virus-fab complex (Complex)
- Chikungunya virus (Virus from Chikungunya virus)
- E3 (6 kDa, Protein from Chikungunya virus)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w1c
Q-score: 0.35
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- Mayaro virus (Virus from Mayaro virus)
- E1 glycoprotein (41 kDa, Protein from Mayaro virus (strain Brazil))
- Mayaro virus-fab chk-265 complex (Complex)
- E2 glycoprotein (38 kDa, Protein from Mayaro virus (strain Brazil))