Hao A, Mao Q, Chen Z, Huang J, Sun L
To Be Published
- Gw01 fv (26 kDa, Protein from Homo sapiens)
- 7f3 fv (27 kDa, Protein from Homo sapiens)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Xbb spike protein (s) in complex with bispecific antibody g7-fc (Complex from Homo sapiens)
10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8sx3
Q-score: 0.378
Schiffner T, Phung I, Ray R, Irimia A, Tian M, Swanson O, Lee JH, Lee CD, Marina-Zarate E, Cho SY, Huang J, Ozorowski G, Skog PD, Serra AM, Rantalainen K, Allen JD, Baboo S, Rodriguez OL, Himansu S, Zhou J, Hurtado J, Flynn CT, McKenney K, Havenar-Daughton C, Saha S, Shields K, Schulze S, Smith ML, Liang CH, Toy L, Pecetta S, Lin YC, Willis JR, Sesterhenn F, Kulp DW, Hu X, Cottrell CA, Zhou X, Ruiz J, Wang X, Nair U, Kirsch KH, Cheng HL, Davis J, Kalyuzhniy O, Liguori A, Diedrich JK, Ngo JT, Lewis V, Phelps N, Tingle RD, Spencer S, Georgeson E, Adachi Y, Kubitz M, Eskandarzadeh S, Elsliger MA, Amara RR, Landais E, Briney B, Burton DR, Carnathan DG, Silvestri G, Watson CT, Yates 3rd JR, Paulson JC, Crispin M, Grigoryan G, Ward AB, Sok D, Alt FW, Wilson IA, Batista FD, Crotty S, Schief WR
Nat Immunol (2024) [ DOI: doi:10.1038/s41590-024-01833-w Pubmed: 38816615 ]
- 10e8 fab heavy chain, 10e8 light chain (Complex from Homo sapiens)
- 10e8 light chain (22 kDa, Protein from Homo sapiens)
- W6-10 mouse fab heavy chain, w6-10 mouse light chain (Complex from Mus musculus)
- 10e8-gt10.2 immunogen (Complex from synthetic construct)
- 10e8-gt10.2 immunogen (21 kDa, Protein from synthetic construct)
- W6-10 mouse fab heavy chain (23 kDa, Protein from Mus musculus)
- 10e8 fab heavy chain (25 kDa, Protein from Homo sapiens)
- 10e8-gt10.2 immunogen in complex with human fab 10e8 and mouse fab w6-10 (Complex)
- W6-10 mouse light chain (23 kDa, Protein from Mus musculus)
CryoEM structure of A/Perth/16/2009 H3 in complex with flu HA central stem VH1-18 antibody UCA6
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ut3
Q-score: 0.58
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D
Immunity (2024) 57 pp. 1141-1159.e11 [ DOI: doi:10.1016/j.immuni.2024.03.022 Pubmed: 38670113 ]
- Hemagglutinin (62 kDa, Protein from Influenza A virus)
- Uca6 lc fv (11 kDa, Protein from Homo sapiens)
- An uca6 fab complex with one protomer of a h3 trimer (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Uca6 hc fv (13 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8ut4
Q-score: 0.433
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D
Immunity (2024) 57 pp. 1141-1159.e11 [ DOI: doi:10.1016/j.immuni.2024.03.022 Pubmed: 38670113 ]
- 09-1b12 hc fv (13 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (28 kDa, Protein from Influenza A virus)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- 09-1b12 fab (Complex from Homo sapiens)
- 09-1b12 lc fv (12 kDa, Protein from Homo sapiens)
- An 09-1b12 fab complex with one protomer of a h1 trimer (Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8ut5
Q-score: 0.439
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D
Immunity (2024) 57 pp. 1141-1159.e11 [ DOI: doi:10.1016/j.immuni.2024.03.022 Pubmed: 38670113 ]
- Uca6_n55t lc fv (11 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (28 kDa, Protein from Influenza A virus)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- An uca6 fab complex with one protomer of a h3 trimer (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Uca6_n55t hc fv (13 kDa, Protein from Homo sapiens)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ut6
Q-score: 0.549
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D
Immunity (2024) 57 pp. 1141-1159.e11 [ DOI: doi:10.1016/j.immuni.2024.03.022 Pubmed: 38670113 ]
- Polyclonal fab purified from mice sera (Complex from Mus musculus)
- H3d15 pfab hc fv_polya (10 kDa, Protein from Mus musculus)
- Hemagglutinin (62 kDa, Protein from Influenza A virus)
- Mice polyclonal fab complex with one protomer of a h3 trimer (Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- H3d15 pfab lc fv_polya (9 kDa, Protein from Mus musculus)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8ut7
Q-score: 0.591
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D
Immunity (2024) 57 pp. 1141-1159.e11 [ DOI: doi:10.1016/j.immuni.2024.03.022 Pubmed: 38670113 ]
- Polyclonal fab purified from mice sera (Complex from Mus musculus)
- Hemagglutinin (62 kDa, Protein from Influenza A virus)
- A/perth/16/2009 h3 (Complex from Influenza A virus)
- H3d28 pfab hc fv_polya (10 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- H3d28 pfab lc fv_polya (9 kDa, Protein from Mus musculus)