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Yeast Set2 bound to a nucleosome containing oncohistone mutations
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7ea5
Q-score: 0.473
Liu Y, Zhang Y, Xue H, Cao M, Bai G, Mu Z, Yao Y, Sun S, Fang D, Huang J
Cell Discov (2021) 7 pp. 32-32 [ Pubmed: 33972509 DOI: doi:10.1038/s41421-021-00261-6 ]
- Histone h3 (11 kDa, Protein from Xenopus laevis)
- The set2-nucleosome(h3k36m)complex structure (Complex from Xenopus laevis)
- Histone h2b (10 kDa, Protein from Xenopus laevis)
- Histone h4 (8 kDa, Protein from Xenopus laevis)
- 601-dna (44 kDa, DNA from synthetic construct)
- Histone-lysine n-methyltransferase, h3 lysine-36 specific (26 kDa, Protein from Saccharomyces cerevisiae)
- 601-dna (44 kDa, DNA from synthetic construct)
- Zinc ion (65 Da, Ligand)
- S-adenosylmethionine (398 Da, Ligand)
- Histone h2a (11 kDa, Protein from Xenopus laevis)
Human SETD2 bound to a nucleosome containing oncohistone mutations
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7ea8
Q-score: 0.509
Liu Y, Zhang Y, Xue H, Cao M, Bai G, Mu Z, Yao Y, Sun S, Fang D, Huang J
Cell Discov (2021) 7 pp. 32-32 [ Pubmed: 33972509 DOI: doi:10.1038/s41421-021-00261-6 ]
- Histone h2a type 1-d (11 kDa, Protein from Homo sapiens)
- 601-dna (37 kDa, DNA from synthetic construct)
- Histone h4 (8 kDa, Protein from Homo sapiens)
- Histone-lysine n-methyltransferase setd2 (28 kDa, Protein from Homo sapiens)
- 601-dna (37 kDa, DNA from synthetic construct)
- Human setd2-ncp(h3.3k36m)-sam complex structure (Complex from Homo sapiens)
- Histone (Complex)
- Histone h3.3 (11 kDa, Protein from Homo sapiens)
- Histone-lysine n-methyltransferase setd2 (Complex from Homo sapiens)
- Dna (Complex)
- Zinc ion (65 Da, Ligand)
- S-adenosylmethionine (398 Da, Ligand)
- Histone h2b type 2-e (13 kDa, Protein from Homo sapiens)
Human SETD2 bound to wild-type nucleosome
Liu Y, Zhang Y, Xue H, Cao M, Bai G, Mu Z, Yao Y, Sun S, Fang D, Huang J
Cell Discov (2021) 7 pp. 32-32 [ Pubmed: 33972509 DOI: doi:10.1038/s41421-021-00261-6 ]
- Setd2-hncp (250 kDa, Complex from Homo sapiens)
Yeast Set2 bound to wild-type nucleosome
Liu Y, Zhang Y, Xue H, Cao M, Bai G, Mu Z, Yao Y, Sun S, Fang D, Huang J
Cell Discov (2021) 7 pp. 32-32 [ Pubmed: 33972509 DOI: doi:10.1038/s41421-021-00261-6 ]
- Yeast set2-ncp complex (200 kDa, Complex from Xenopus laevis)