Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Han Y" AND citation_journal_name:"TO BE PUBLISHED"

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EMD-40456

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Cryo-EM structure of human NCX1 in complex with SEA0400

Release date: April 24, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8sgi
Q-score: 0.553

Xue J, Han Y, Zeng W, Jiang Y

To Be Published

Sample:

Human cardiac sodium calcium exchanger ncx1 in complex with sea0400 (Complex from Homo sapiens)
Fab heavy chain (26 kDa, Protein from Mus musculus)
Calcium ion (40 Da, Ligand)
Fab light chain (21 kDa, Protein from Mus musculus)
Human ncx1-sea0400 in complex with antibody fab fragment (Complex)
Sodium ion (22 Da, Ligand)
Water (18 Da, Ligand)
Sodium/calcium exchanger 1 (109 kDa, Protein from Homo sapiens)
Antibody fab fragment (Complex from Mus musculus)
2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline (371 Da, Ligand)

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