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Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8t4k
Q-score: 0.62
Steichen JM, Phung I, Salcedo E, Ozorowski G, Willis JR, Baboo S, Liguori A, Cottrell CA, Torres JL, Madden PJ, Ma KM, Sutton HJ, Lee JH, Kalyuzhniy O, Allen JD, Rodriguez OL, Adachi Y, Mullen TM, Georgeson E, Kubitz M, Burns A, Barman S, Mopuri R, Metz A, Altheide TK, Diedrich JK, Saha S, Shields K, Schultze SE, Smith ML, Schiffner T, Burton DR, Watson CT, Bosinger SE, Crispin M, Yates 3rd JR, Paulson JC, Ward AB, Sok D, Crotty S, Schief WR
Science (2024) 384 pp. eadj8321-eadj8321 [ Pubmed: 38753769 DOI: doi:10.1126/science.adj8321 ]
- Md64 n332-gt5 sosip (Complex from Human immunodeficiency virus 1)
- Md64 n332-gt5 sosip gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Md64 n332-gt5 sosip gp41 (18 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
HIV-1 Env subtype C CZA97.12 SOSIP.664 in complex with 3BNC117 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8gje
Q-score: 0.451
Ringe RP, Colin P, Ozorowski G, Allen JD, Yasmeen A, Seabright GE, Lee JH, Antanasijevic A, Rantalainen K, Ketas T, Moore JP, Ward AB, Crispin M, Klasse PJ
PLoS Pathog (2023) 19 pp. e1011601-e1011601 [ Pubmed: 37903160 DOI: doi:10.1371/journal.ppat.1011601 ]
- Cza97.12 sosip.664 envelope glycoprotein gp120 (56 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cza97.12 sosip.664 in complex with 3bnc117 fab (570 kDa, Complex)
- Cza97.12 sosip.664 envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 3bnc117 fab heavy chain (24 kDa, Protein from Homo sapiens)
- 3bnc117 kappa light chain (23 kDa, Protein from Homo sapiens)
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP2
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost2 SOSIP.664 in complex with NHP Polyclonal Antibody FP4
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost 2 in complex with NHP antibody V1V2
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost 2 in complex with NHP Polyclonal Antibody N625
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody Base1
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
Boost 2 SOSIP.664 in complex with NHP polyclonal antibody Base2
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody Base3
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8sw7
Q-score: 0.444
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB
bioRxiv (2023) [ Pubmed: 37425865 DOI: doi:10.1101/2023.06.26.545779 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 boost 2 in complex with nhp polyclonal antibody fp1 (470 kDa, Complex from Human immunodeficiency virus 1)
- Bg505 boost 2 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Fp1 light chain (9 kDa, Protein from Macaca mulatta)
- Bg505 boost 2 gp120 (58 kDa, Protein from Human immunodeficiency virus 1)
- Fp1 heavy chain (10 kDa, Protein from Macaca mulatta)