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author:"Belousoff MJ" AND assembly_molecular_weight:{1000000 TO 2000000]
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50S ribosomal subunit from Staphylococcus aureus (Strain ATCC43300)

Release date: July 6, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7ttu
Q-score: 0.447

Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T, Belousoff MJ

Microbiol Spectr (2022) 10 pp. e0058322-e0058322 [ Pubmed: 35736238 DOI: doi:10.1128/spectrum.00583-22 ]

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50S ribosomal subunit from Staphylococcus aureus containing double mutation in uL3 imparting linezolid resistance

Release date: July 6, 2022
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7ttw
Q-score: 0.598

Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T, Belousoff MJ

Microbiol Spectr (2022) 10 pp. e0058322-e0058322 [ Pubmed: 35736238 DOI: doi:10.1128/spectrum.00583-22 ]

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Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid

Release date: June 3, 2020
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6wqn
Q-score: 0.601

Wright A, Deane-Alder K, Marschall E, Bamert R, Venugopal H, Lithgow T, Lupton DW, Belousoff MJ

Acs Pharmacol Transl Sci (2020) 3 pp. 425-432 [ DOI: doi:10.1021/acsptsci.0c00041 Pubmed: 32566908 ]

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Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid

Release date: June 3, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wqq
Q-score: 0.571

Wright A, Deane-Alder K, Marschall E, Bamert R, Venugopal H, Lithgow T, Lupton DW, Belousoff MJ

Acs Pharmacol Transl Sci (2020) 3 pp. 425-432 [ DOI: doi:10.1021/acsptsci.0c00041 Pubmed: 32566908 ]

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Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid

Release date: June 3, 2020
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6wrs
Q-score: 0.561

Wright A, Deane-Alder K, Marschall E, Bamert R, Venugopal H, Lithgow T, Lupton DW, Belousoff MJ

Acs Pharmacol Transl Sci (2020) 3 pp. 425-432 [ DOI: doi:10.1021/acsptsci.0c00041 Pubmed: 32566908 ]

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Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid

Release date: June 3, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wru
Q-score: 0.567

Wright A, Deane-Alder K, Marschall E, Bamert R, Venugopal H, Lithgow T, Lupton DW, Belousoff MJ

Acs Pharmacol Transl Sci (2020) 3 pp. 425-432 [ DOI: doi:10.1021/acsptsci.0c00041 Pubmed: 32566908 ]

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Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-5

Release date: March 20, 2019
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ddd
Q-score: 0.554

Belousoff MJ, Venugopal H, Wright A, Seoner S, Stuart I, Stubenrauch C, Bamert RS, Lupton DW, Lithgow T

Chem Med Chem (2019) 14 pp. 527-531 [ DOI: doi:10.1002/cmdc.201900042 Pubmed: 30667174 ]

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Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-6

Release date: March 20, 2019
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ddg
Q-score: 0.562

Belousoff MJ, Venugopal H, Wright A, Seoner S, Stuart I, Stubenrauch C, Bamert RS, Lupton DW, Lithgow T

Chem Med Chem (2019) 14 pp. 527-531 [ DOI: doi:10.1002/cmdc.201900042 Pubmed: 30667174 ]

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Methicillin Resistant, Linezolid resistant Staphylococcus aureus 70S ribosome (delta S145 uL3)

Release date: May 31, 2017
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5t7v
Q-score: 0.462

Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert RS, Matzov D, Bashan A, Zimmerman E, Mishra S, Cameron D, Elmlund H, Peleg AY, Bhushan S, Lithgow T, Yonath A

mBio (2017) 8 [ Pubmed: 28487427 DOI: doi:10.1128/mBio.00395-17 ]

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