EMD-23708

Single-particle
3.93 Å
EMD-23708
3D View Gallery
Deposition: 26/03/2021
Map released: 15/12/2021
Last modified: 22/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-23708
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7m74 summary report (pdf.gz) Map and 7m74 FULL report (pdf.gz)
EMICSS annotations (xml)

ATP-bound AMP-activated protein kinase

EMD-23708

Single-particle
3.93 Å
EMD-23708
3D View Gallery
Deposition: 26/03/2021
Map released: 15/12/2021
Last modified: 22/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Escherichia coli, Lama glama
Sample: MBP-fused ATP bound AMPK in complex with C-compound stabilized by Fab and a nanobody
Fitted models: 7m74

Deposition Authors: Yan Y , Mukherjee S , Harikumar KG , Strutzenberg T, Zhou XE , Powell SK, Xu T, Sheldon R, Lamp J , Brunzelle JS , Radziwon K, Ellis A , Novick SJ , Vega IE, Jones R, Miller LJ , Xu HE , Griffin PR , Kossiakoff AA, Melcher K
Structure of an AMPK complex in an inactive, ATP-bound state.
Yan Y , Mukherjee S , Harikumar KG , Strutzenberg TS , Zhou XE , Suino-Powell K, Xu TH , Sheldon RD , Lamp J , Brunzelle JS , Radziwon K, Ellis A , Novick SJ , Vega IE, Jones RG , Miller LJ , Xu HE , Griffin PR , Kossiakoff AA, Melcher K
(2021) Science , 373 , 413 - 419
PUBMED: 34437114
DOI: doi:10.1126/science.abe7565
ISSN: 1095-9203
ASTM: SCIEAS