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EMD-36229
CryoEM structure of Gi-coupled MRGPRX1 with peptide agonist CNF-Tx2
EMD-36229
Single-particle2.84 Å
Deposition: 20/05/2023Map released: 10/01/2024
Last modified: 10/01/2024
Sample Organism:
Homo sapiens,
Conus textile
Sample: Cryo-EM structure of the BAM8-22-bound MRGPRX1-Gq complex
Fitted models: 8jgb
Deposition Authors: Sun JP
,
Xu HE,
Yang F ,
Liu ZM,
Guo LL,
Zhang YM,
Fang GX,
Tie L ,
Zhuang YM,
Xue CY
Sample: Cryo-EM structure of the BAM8-22-bound MRGPRX1-Gq complex
Fitted models: 8jgb
Deposition Authors: Sun JP
,
Xu HE,
Yang F ,
Liu ZM,
Guo LL,
Zhang YM,
Fang GX,
Tie L ,
Zhuang YM,
Xue CY
Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Guo L,
Zhang Y,
Fang G,
Tie L ,
Zhuang Y,
Xue C ,
Liu Q,
Zhang M,
Zhu K,
You C,
Xu P ,
Yuan Q,
Zhang C,
Liu L,
Rong N,
Peng S,
Liu Y,
Wang C ,
Luo X,
Lv Z,
Kang D ,
Yu X ,
Zhang C,
Jiang Y,
Dong X,
Zhou J,
Liu Z ,
Yang F ,
Eric Xu H ,
Sun JP
(2023) Nat Commun , 14 , 5004 - 5004
,
Zhuang Y,
Xue C ,
Liu Q,
Zhang M,
Zhu K,
You C,
Xu P ,
Yuan Q,
Zhang C,
Liu L,
Rong N,
Peng S,
Liu Y,
Wang C ,
Luo X,
Lv Z,
Kang D ,
Yu X ,
Zhang C,
Jiang Y,
Dong X,
Zhou J,
Liu Z ,
Yang F ,
Eric Xu H ,
Sun JP
(2023) Nat Commun , 14 , 5004 - 5004