Ligand clusters for UniProt code P00636

Ligand clusters for P00636: Fructose-1,6-bisphosphatase 1 OS=Sus scrofa GN=FBP1 PE=1 SV=4

		6 ligand clusters Cluster 1. 15 ligand types 232 ligands Cluster 2. 6 ligand types 36 ligands Cluster 3. 8 ligand types 52 ligands Cluster 4. 2 ligand types 2 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 1fsaA

Structures

PDB		Schematic diagram
1fsaA
1rdxA
4gx3A
2qvuA
2qvvA
		more ...

Cluster 1 contains 15 ligand types

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Ligand		Description
		1. Ligand: F6P × 30 Fructose-6-Phosphate PDB codes: 1cnq(A), 1eyi(A), 1eyj(A), 1eyk(A), 1fbp(A), 1fj6(A), 1fj9(A), 1fsa(A), 1kz8(A), 1lev(A), 1nuw(A), 1nux(A), 1nuy(A), 1nuz(A), 1nv0(A), 1nv1(A), 1nv3(A), 1nv4(A), 1nv5(A), 1nv7(A), 1q9d(A), 1rdx(A), 1rdy(A), 1rdz(A), 1yxi(A), 1yyz(A), 1yz0(A), 2f3b(A), 2f3d(A), 5fbp(A).
		2. Ligand: PO4 × 19 Phosphate ion PDB codes: 1cnq(A), 1eyi(A), 1eyj(A), 1eyk(A), 1fj6(A), 1fj9(A), 1nuy(A), 1nuz(A), 1nv0(A), 1nv1(A), 1nv3(A), 1nv4(A), 1nv5(A), 1nv7(A), 1q9d(A), 1yxi(A), 1yyz(A), 2f3b(A), 2f3d(A).
_Mg		3. Metal: _MG × 61 PDB codes: 1eyi(A), 1eyj(A), 1fbc(A), 1fbf(A), 1fbp(A), 1nuw(A), 1nux(A), 1nuy(A), 1nuz(A), 1nv0(A), 1nv1(A), 1nv3(A), 1nv4(A), 1nv5(A), 1nv7(A), 1q9d(A), 1yxi(A), 1yyz(A), 1yz0(A), 2qvu(A), 4gws(A), 4gwu(A), 4gww(A), 4gwx(A), 4gwy(A), 4gwz(A), 4gx3(A), 4gx4(A), 4gx6(A), 4h46(A), 4kxp(A),
_Mn		4. Metal: _MN × 20 PDB codes: 1fbd(A), 1fbg(A), 1fpd(A), 1fpe(A), 1fpf(A), 1fpg(A), 1fsa(A), 1kz8(A), 1lev(A), 4gbv(A), 4gbw(A),
__K		5. Metal: __K × 3 PDB codes: 1fpi(A),
		6. Ligand: AHG × 10 2,5-Anhydroglucitol-1,6-Biphosphate PDB codes: 1fbc(A), 1fbd(A), 1fbe(A), 1fpd(A), 1fpe(A), 1fpf(A), 1fpg(A), 1fpi(A), 1fpj(A), 1fpl(A).
		7. Ligand: AHM × 2 2,5-Anhydromannitol-1,6-Diphosphate PDB codes: 1fbf(A), 1fbg(A).
		8. Ligand: FDP × 5 Fructose-2,6-Diphosphate PDB codes: 1fpb(A), 1frp(A), 2qvu(A), 2qvv(A), 3fbp(A).
		9. Ligand: PO3 × 2 Phosphite ion PDB codes: 1nuw(A), 1nux(A).
		10. Ligand: F6P × 13 Fructose-6-Phosphate PDB codes: 4gbv(A), 4gbw(A), 4gws(A), 4gww(A), 4gwx(A), 4gwy(A), 4gwz(A), 4gx3(A), 4gx4(A), 4gx6(A), 4h45(A), 4h46(A), 4kxp(A).
		11. Ligand: PO4 × 13 Phosphate ion PDB codes: 4gbv(A), 4gbw(A), 4gws(A), 4gww(A), 4gwx(A), 4gwy(A), 4gwz(A), 4gx3(A), 4gx4(A), 4gx6(A), 4h45(A), 4h46(A), 4kxp(A).
_Tl		12. Metal: _TL × 31 PDB codes: 1fpj(A), 1fpk(A), 1fpl(A), 1nv0(A), 1nv1(A), 1nv3(A), 1nv4(A), 1nv5(A), 1nv7(A),
_Zn		13. Metal: _ZN × 21 PDB codes: 1cnq(A), 1eyk(A), 1fbe(A), 1fj6(A), 1fj9(A), 1frp(A), 2f3b(A), 2f3d(A), 2qvv(A), 4h45(A),
		14. Ligand: FDP × 1 Fructose-2,6-Diphosphate PDB code: 4gwu(A).
		15. Ligand: AFP-FBP × 1 AFP=Alpha fructose 1,6-Diphosphate, FBP=Beta-Fructose-1,6-Diphosphate. PDB code: 1fbh(A).

Cluster 2 contains 6 ligand types

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Ligand		Description
		1. Ligand: F6P × 12 Fructose-6-Phosphate PDB codes: 1eyj(A), 1eyk(A), 1fbp(A), 1fj9(A), 1fsa(A), 1kz8(A), 1lev(A), 1nv7(A), 1q9d(A), 1rdx(A), 1yz0(A), 5fbp(A).
		2. Ligand: AHG × 10 2,5-Anhydroglucitol-1,6-Biphosphate PDB codes: 1fbc(A), 1fbd(A), 1fbe(A), 1fpd(A), 1fpe(A), 1fpf(A), 1fpg(A), 1fpi(A), 1fpj(A), 1fpl(A).
		3. Ligand: AHM × 2 2,5-Anhydromannitol-1,6-Diphosphate PDB codes: 1fbf(A), 1fbg(A).
		4. Ligand: FDP × 5 Fructose-2,6-Diphosphate PDB codes: 1fpb(A), 1frp(A), 2qvu(A), 2qvv(A), 3fbp(A).
		5. Ligand: F6P × 6 Fructose-6-Phosphate PDB codes: 4gws(A), 4gwz(A), 4gx3(A), 4gx4(A), 4gx6(A), 4kxp(A).
		6. Ligand: AFP-FBP × 1 AFP=Alpha fructose 1,6-Diphosphate, FBP=Beta-Fructose-1,6-Diphosphate. PDB code: 1fbh(A).

Cluster 3 contains 8 ligand types

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Ligand		Description
		1. Ligand: PO4 × 14 Phosphate ion PDB codes: 1eyi(A), 1fj6(A), 1nuy(A), 1nuz(A), 1nv0(A), 1nv1(A), 1nv3(A), 1nv4(A), 1nv5(A), 1q9d(A), 1yxi(A), 2f3b(A), 2qvu(A), 2qvv(A).
		2. Ligand: F6P × 2 Fructose-6-Phosphate PDB codes: 1cnq(A), 5fbp(A).
		3. Ligand: FDP × 1 Fructose-2,6-Diphosphate PDB code: 1fpb(A).
		4. Ligand: AMP × 21 Adenosine monophosphate PDB codes: 1eyj(A), 1eyk(A), 1fbp(A), 1fj9(A), 1fpd(A), 1fpe(A), 1fpf(A), 1fpg(A), 1fpi(A), 1fpj(A), 1fpl(A), 1frp(A), 1fsa(A), 1kz8(A), 1nv7(A), 1rdy(A), 1rdz(A), 1yyz(A), 1yz0(A), 2f3d(A), 4fbp(A).
		5. Ligand: CLI × 1 3-(2-Carboxy-Ethyl)-4,6-Dichloro-1h-Indole-2-Carboxylic acid PDB code: 1lev(A).
		6. Ligand: AMP × 9 Adenosine monophosphate PDB codes: 4gbv(A), 4gbw(A), 4gws(A), 4gwy(A), 4gwz(A), 4gx4(A), 4gx6(A), 4h46(A), 4kxp(A).
		7. Ligand: PO4 × 3 Phosphate ion PDB codes: 4gwx(A), 4gx3(A), 4h45(A).
		8. Ligand: F6P × 1 Fructose-6-Phosphate PDB code: 4gww(A).

Cluster 4 contains 2 ligand types

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Ligand		Description
		1. Ligand: OI1 × 1 3-(4-Hydroxybenzyl)-2-[1-({[2-(4-Hydroxyphenyl) ethyl]amino}carbonyl)butyl]-4-Oxo-3,6,11,11a- Tetrahydro-4h-Pyrazino[1,2-B]isoquinolin-2-Ium-1-Olate PDB code: 1q9d(A).
		2. Ligand: PFE × 1 {4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]- Thiazol-2-Yl}-Methanol PDB code: 1kz8(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: OI1 × 1 3-(4-Hydroxybenzyl)-2-[1-({[2-(4-Hydroxyphenyl) ethyl]amino}carbonyl)butyl]-4-Oxo-3,6,11,11a- Tetrahydro-4h-Pyrazino[1,2-B]isoquinolin-2-Ium-1-Olate PDB code: 1q9d(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: NEN × 1 1-Ethyl-Pyrrolidine-2,5-Dione PDB code: 4h46(A).