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Crystal Structure of Human DJ-1

X-ray diffraction
2.5Å resolution
PDB entry 1j42 coloured by chain, front view.
PDB entry 1j42 coloured by chain, side view.
PDB entry 1j42 coloured by chain, top view.
Source organism: Homo sapiens
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Parkinson disease protein 7
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Multimeric state: monomeric
Accessible surface area: 8410.64 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-189205
Assembly 2
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Assembly Name: Parkinson disease protein 7
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Multimeric state: homo dimer
Accessible surface area: 14302.41 Å2
Buried surface area: 2516.37 Å2
Dissociation area: 1,258.19 Å2
Dissociation energy (ΔGdiss): 13.62 kcal/mol
Dissociation entropy (TΔSdiss): 12.26 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-189207

Macromolecules

Parkinson disease protein 7
Chain: A
Length: 189 amino acids
Theoretical weight: 19.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99497 (Residues: 1-189; Coverage: 100%)
Gene name: PARK7
Pfam: DJ-1/PfpI family
InterPro:
CATH: Rossmann fold
SCOP: DJ-1/PfpI
Parkinson disease protein 7 in PDB entry 1j42, assembly 1, front view.
Parkinson disease protein 7 in PDB entry 1j42, assembly 1, side view.
Parkinson disease protein 7 in PDB entry 1j42, assembly 1, top view.
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