DJ-1/PfpI (IPR002818)

Short name: DJ-1/PfpI

Overlapping homologous superfamilies

Domain relationships



The domain is found in intracellular cysteine peptidase PfpI [PMID: 8626329] and other members of the DJ-1/ThiJ/PfpI superfamily [PMID: 14745011]. Some of these have been characterised:

  • Pyrococcus horikoshii PH1704, which has both aminopeptidase and endopeptidase activity [PMID: 25192005].
  • Arabidopsis thaliana DJ1D, which has glyoxalase I activity [PMID: 23651081].
  • Candida albicans glyoxalase 3 [PMID: 24302734].

It is also found in transcriptional regulators in combination with a HTH(araC) domain, such as in Pseudomonas aeruginosa cdhR [PMID: 19406895].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.