Structure for phosphoramidon (M04.001 inhibitor)
 
| PDB | Organism | Resolution | Comment |
|---|---|---|---|
| 1DMT_A | Homo sapiens | 2.10 Å | complex with phosphoramidon |
| The catalytic zinc is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His583 and His587 in purple and Glu646 in blue. The catalytic residues are shown in ball-and-stick representation: Glu584 in blue and Asp650 in pink. Carbohydrates are shown as CPK spheres in yellow. | |||
![]() |
|||
| Show surface | |||
![]() |
|||
| 1TLP | Bacillus thermoproteolyticus | 2.30 Å | complex with phosphoramidon |
| The catalytic zinc is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His374 and His378 in purple and Glu398 in blue. The catalytic Glu375 is shown in blue. Phosphoramidon is shown in grey. | |||
![]() |
Get the latest Java Plug-in here. |
||
| Show surface | |||
![]() |
|||
| 3DWB | Homo sapiens | 2.38 Å | complex with phosphoramidon |
| The catalytic zinc atom is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His607 and His611 in purple, Glu667 in blue. The catalytic residues are shown in ball-and-stick representation: Glu608 in blue and Asp671 in pink. The bound inhibitor is shown in grey ball-and-stick representation. | |||
![]() |
Get the latest Java Plug-in here. |
||
| Show surface | |||
![]() |
|||
| 3ZUK | Mycobacterium tuberculosis | 2.60 Å | complex with phosphoramidon |
| The catalytic zinc atom is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His387 and His391 in purple, Glu454 in blue. The catalytic residues are shown in ball-and-stick representation: Glu388 in blue and Asp458 in pink. The bound inhibitor is shown in grey ball-and-stick representation. | |||
![]() |
Get the latest Java Plug-in here. |
||
| Show surface | |||
![]() |
|||
| TERTIARY STRUCTURE DATA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
| thermolysin ( Bacillus thermoproteolyticus) | ||||||||
| complex with phosphoramidon | 2.30 Å | 1TLP | 1TLP | 1TLP | 1TLP | 1TLP | 1TLP | Tronrud et al., 1986 |
| neprilysin ( Homo sapiens) | ||||||||
| complex with phosphoramidon | 2.10 Å | 1DMT | 1DMT | 1DMT | 1DMT | 1DMT | 1DMT | Oefner et al., 2000 |
| endothelin-converting enzyme 1 ( Homo sapiens) | ||||||||
| complex with phosphoramidon | 2.38 Å | 3DWB | 3DWB | 3DWB | 3DWB | 3DWB | 3DWB | Schulz et al., 2009 |
| farnesylated-protein converting enzyme 1 ( Homo sapiens) | ||||||||
| complex with phosphoramidon | 3.85 Å | 6BH8 | 6BH8 | 6BH8 | 6BH8 | 6BH8 | 6BH8 | |
| Zmp1 peptidase (Mycobacterium-type) ( Mycobacterium tuberculosis) | ||||||||
| complex with phosphoramidon | 2.60 Å | 3ZUK | 3ZUK | 3ZUK | 3ZUK | 3ZUK | 3ZUK | Ferraris et al., 2011 |
| neprilysin ( Oryctolagus cuniculus) | ||||||||
| complex with phosphoramidon | 2.80 Å | 4ZR5 | 4ZR5 | 4ZR5 | 4ZR5 | 4ZR5 | 4ZR5 | |
| pseudolysin ( Pseudomonas aeruginosa) | ||||||||
| complex with phosphoramidon | 1.40 Å | 3DBK | 3DBK | 3DBK | 3DBK | 3DBK | 3DBK | |








