Structure for carfilzomib (T01.010, T01.011, T01.012 inhibitor)
 
| TERTIARY STRUCTURE DATA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
| proteasome subunit alpha 6 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit alpha 2 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit alpha 4 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit alpha 7 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit alpha 5 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit alpha 1 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit alpha 3 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit beta1c ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| protein serine kinase c17 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit beta 3 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit beta 2 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit beta 1 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit beta 4 ( Homo sapiens) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
| proteasome subunit beta5i ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit beta 1 ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit beta5c ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit beta 1 ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit beta5c ( Mus musculus) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| subfamily T1A unassigned peptidases ( Mus musculus) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with carfilzomib | 2.80 Å | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | 4QW4 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with carfilzomib | 3.00 Å | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | 4QW5 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with carfilzomib | 2.90 Å | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | 4QW6 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with carfilzomib | 2.70 Å | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | 4QW7 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with carfilzomib | 3.00 Å | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | 4QWF | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with carfilzomib | 2.60 Å | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | 4QWG | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with carfilzomib | 2.60 Å | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | 4QWI | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with carfilzomib | 2.90 Å | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | 4QWJ | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr, Ala50Val mutant; complex with carfilzomib | 2.80 Å | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | 4QWK | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with carfilzomib | 2.60 Å | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | 4QWL | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with carfilzomib | 2.90 Å | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | 4QWR | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with carfilzomib | 3.00 Å | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | 4QWS | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a mutant in complex with carfilzomib | 2.80 Å | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | 5CZ5 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49)s-k33a mutant in complex with carfilzomib | 2.80 Å | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | 5CZ8 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d17n mutant in complex with carfilzomib; propeptide expressed in trans | 2.90 Å | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | 5CZ9 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-d166n mutant in complex with carfilzomib | 2.50 Å | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | 5D0S | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1c mutant in complex with carfilzomib | 2.90 Å | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | 5D0V | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with carfilzomib | 2.90 Å | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | 5D0Z | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)l-t1a double mutant in complex with carfilzomib | 2.80 Å | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | 5FGD | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)t-t1a double mutant in complex with carfilzomib | 2.60 Å | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | 5FGE | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-h(-2)a-t1a-k81r triple mutant in complex with carfilzomib | 2.60 Å | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | 5FGF | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-l(-49s)_d17n double mutant in complex with carfilzomib | 2.70 Å | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | 5FGG | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta1-t1a beta2-t1a double mutant in complex withcarfilzomib | 2.90 Å | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | 5FGI | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-k33a mutant (propeptide expressed in trans)in complex with carfilzomib | 2.70 Å | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | 5FHS | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | 5L5E | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib | 2.70 Å | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | 5L5Y | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with carfilzomib | 2.90 Å | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | 5L65 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with carfilzomib | 2.30 Å | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | 6HWE | |
