Structure for GRL-05010 (A02.001 inhibitor)

Summary Structure Literature

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
HIV-1 retropepsin ( human immunodeficiency virus 1)
wild type; complex with GRL-050-10a (a gem-difluoro-bis- tetrahydrofuran as p2-ligand) 1.30 Å 4U8W 4U8W 4U8W 4U8W 4U8W 4U8W
Leu76Val mutant; complex with GRL-5010 (gem- difluoro-bis-tetrahydrofuran as p2 ligand) 1.31 Å 6DJ7 6DJ7 6DJ7 6DJ7 6DJ7 6DJ7