Structure for inhibitor I13.003: chymotrypsin inhibitor 2

Summary Alignment Sequences Sequence features Distribution Structure Literature

PDB	Organism	Resolution	Comment
2CI2	Hordeum vulgare	2.00 Å	mature
The reactive site Met59 is shown in green ball-and-stick representation.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Hordeum vulgare
complex of fragments 1-40 and 41-64	2.20 Å	1CIQ	1CIQ	1CIQ	1CIQ	1CIQ	1CIQ	Neira et al., 1996
NMR structure; complex of fragments 1-40 and 41-64	0.00 Å	1CIR	1CIR	1CIR	1CIR	1CIR	1CIR	Neira et al., 1996
mature inhibitor	0.00 Å	1CIS	1CIS	1CIS	1CIS	1CIS	1CIS	Osmark et al., 1993
Ile76Val mutant	2.20 Å	1COA	1COA	1COA	1COA	1COA	1COA	Jackson et al., 1993
Met59 replaced by tetraglutamine mutant	1.80 Å	1CQ4	1CQ4	1CQ4	1CQ4	1CQ4	1CQ4	Chen et al., 1999
complex with subtilisin BPN'	1.50 Å	1LW6	1LW6	1LW6	1LW6	1LW6	1LW6	Radisky & Koshland, 2002
complex with subtilisin BPN'	1.70 Å	1TM1	1TM1	1TM1	1TM1	1TM1	1TM1	Radisky et al., 2004
Met59Lys mutant; complex with subtilisin BPN'	1.57 Å	1TM3	1TM3	1TM3	1TM3	1TM3	1TM3	Radisky et al., 2004
Met59Gly mutant; complex with subtilisin BPN'	1.70 Å	1TM4	1TM4	1TM4	1TM4	1TM4	1TM4	Radisky et al., 2004
Met59Ala mutant; complex with subtilisin BPN'	1.45 Å	1TM5	1TM5	1TM5	1TM5	1TM5	1TM5	Radisky et al., 2004
Met59Tyr mutant; complex with subtilisin BPN'	1.59 Å	1TM7	1TM7	1TM7	1TM7	1TM7	1TM7	Radisky et al., 2004
Met59Phe mutant; complex with subtilisin BPN'	1.67 Å	1TMG	1TMG	1TMG	1TMG	1TMG	1TMG	Radisky et al., 2004
Tyr61Ala mutant; complex with subtilisin BPN'	1.68 Å	1TO1	1TO1	1TO1	1TO1	1TO1	1TO1	Radisky et al., 2004
Met59Lys mutant; complex with subtilisin BPN' at pH 9	1.30 Å	1TO2	1TO2	1TO2	1TO2	1TO2	1TO2	Radisky et al., 2004
Thr58Ala mutant; complex with subtilisin BPN'	1.56 Å	1Y1K	1Y1K	1Y1K	1Y1K	1Y1K	1Y1K	Radisky et al., 2005
Thr58Pro mutant; complex with subtilisin BPN'	1.80 Å	1Y33	1Y33	1Y33	1Y33	1Y33	1Y33	Radisky et al., 2005
Glu60Ala mutant; complex with subtilisin BPN'	1.55 Å	1Y34	1Y34	1Y34	1Y34	1Y34	1Y34	Radisky et al., 2005
Glu60Ser mutant; complex with subtilisin BPN'	1.80 Å	1Y3B	1Y3B	1Y3B	1Y3B	1Y3B	1Y3B	Radisky et al., 2005
Arg62Ala mutant; complex with subtilisin BPN'	1.69 Å	1Y3C	1Y3C	1Y3C	1Y3C	1Y3C	1Y3C	Radisky et al., 2005
Arg67Ala mutant; complex with subtilisin BPN'	1.80 Å	1Y3D	1Y3D	1Y3D	1Y3D	1Y3D	1Y3D	Radisky et al., 2005
Phe69Ala mutant; complex with subtilisin BPN'	1.72 Å	1Y3F	1Y3F	1Y3F	1Y3F	1Y3F	1Y3F	Radisky et al., 2005
Arg65Ala mutant; complex with subtilisin BPN'	1.84 Å	1Y48	1Y48	1Y48	1Y48	1Y48	1Y48	Radisky et al., 2005
Met59Arg, Glu60Ser mutant; complex with subtilisin BPN'	1.60 Å	1Y4A	1Y4A	1Y4A	1Y4A	1Y4A	1Y4A	Radisky et al., 2005
Ser31Ala, Glu33Ala and Glu34Ala mutant	2.00 Å	1YPA	1YPA	1YPA	1YPA	1YPA	1YPA	Harpaz et al., 1994
Ser31Gly, Glu33Ala and Glu34Ala mutant	2.00 Å	1YPB	1YPB	1YPB	1YPB	1YPB	1YPB	Harpaz et al., 1994
Glu33Ala and Glu34Ala mutant	1.70 Å	1YPC	1YPC	1YPC	1YPC	1YPC	1YPC	Harpaz et al., 1994
mature inhibitor	2.00 Å	2CI2	2CI2	2CI2	2CI2	2CI2	2CI2	McPhalen & James, 1987
complex with subtilisin BPN'	2.10 Å	2SNI	2SNI	2SNI	2SNI	2SNI	2SNI	McPhalen & James, 1988
NMR structure	0.00 Å	3CI2	3CI2	3CI2	3CI2	3CI2	3CI2	Ludvigsen et al., 1991
structure of subtilase subhal from bacillus halmapalus - complex with chymotrypsin inhibitor ci2a	1.90 Å	5FBZ	5FBZ	5FBZ	5FBZ	5FBZ	5FBZ
complex of subtilase subty from bacillus sp. ty145 with chymotrypsin inhibitor ci2a	1.80 Å	5FFN	5FFN	5FFN	5FFN	5FFN	5FFN