Small-molecule inhibitor: ASP8497

Summary Literature

Name

Common name: ASP8497

Inhibition

Peptidases inhibited: dipeptidyl-peptidase IV (Tahara et al., 2009).
Pharmaceutical relevance: Has antidiabetic activity in a mouse model (Matsuyama-Yokono et al., 2009).

Chemistry

Structure
Chemical/biochemical name: (2S,4S)-4-fluoro-1-({[4-methyl-1-(methylsulfonyl)piperidin-4-yl]amino}acetyl)pyrrolidine-2-carbonitrile monofumarate.