Small-molecule inhibitor: rivaroxaban
Name
- Common name
- rivaroxaban
- Other names
- BAY 59-7939; Xarelto
Inhibition
- Peptidases inhibited
- Rivaroxaban inhibits coagulation factor Xa reversibly. Endogenous factor Xa was inhibited more potently in human and rabbit plasma (IC50 21 nm) than in rat plasma (IC50 290 nm) (Perzborn et al., 2005).
Chemistry
- CID at PubChem
- 9875401
- Structure
- Chemical/biochemical name
- 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
- Formula weight
- 436
![[rivaroxaban (S01.216 inhibitor) structure ]](http://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&cid=9875401)
