Literature for semagacestat (A22.001 inhibitor)
(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)
-
Tagami,S., Yanagida,K., Kodama,T.S., Takami,M., Mizuta,N., Oyama,H., Nishitomi,K., Chiu,Y.W., Okamoto,T., Ikeuchi,T., Sakaguchi,G., Kudo,T., Matsuura,Y., Fukumori,A., Takeda,M., Ihara,Y. and Okochi,M.
Semagacestat is a pseudo-inhibitor of gamma-secretase
Cell Rep21, 259-273. PubMed Europe PubMed DOI I -
De Strooper,B. and Chavez Gutierrez,L.
Learning by failing: ideas and concepts to tackle gamma-secretases in Alzheimer's disease and beyond
Annu Rev Pharmacol Toxicol55, 419-437. PubMed Europe PubMed DOI I -
De Strooper,B.
Lessons from a failed gamma-secretase Alzheimer trial
Cell159, 721-726. PubMed Europe PubMed DOI I -
Imbimbo,B.P., Panza,F., Frisardi,V., Solfrizzi,V., D'Onofrio,G., Logroscino,G., Seripa,D. and Pilotto,A.
Therapeutic intervention for Alzheimer's disease with gamma-secretase inhibitors: still a viable option?
Expert Opin Investig Drugs20, 325-341. PubMed Europe PubMed DOI I -
Ross,J.S. and Imbimbo,B.P.
Are gamma-secretase inhibitors detrimental for Alzheimer's disease patients?
J Alzheimers Dis22, 401-404. PubMed Europe PubMed DOI I -
Imbimbo,B.P.
Alzheimer's disease: gamma-secretase inhibitors
Drug Discov Today Ther Strateg5, 169-175. DOI I -
[YEAR:11-8-2006]Clarke,E.E., Churcher,I., Ellis,S., Wrigley,J.D., Lewis,H.D., Harrison,T., Shearman,M.S. and Beher,D.
Intra- or intercomplex binding to the gamma-secretase enzyme. A model to differentiate inhibitor classes
J Biol Chem281, 31279-31289. PubMed Europe PubMed DOI I -
[YEAR:28-2-2006]Siemers,E.R., Quinn,J.F., Kaye,J., Farlow,M.R., Porsteinsson,A., Tariot,P., Zoulnouni,P., Galvin,J.E., Holtzman,D.M., Knopman,D.S., Satterwhite,J., Gonzales,C., Dean,R.A. and May,P.C.
Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease
Neurology66, 602-604. PubMed Europe PubMed DOI I
2017
2015
2014
2011
2010
2008
2006
