Literature for aliskiren (A01.007 inhibitor)
(Topics flags: S Structure, T Target, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)
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Nakano,D. and Nishiyama,A.
A novel role of renin inhibitor in the complement cascade
Kidney Int94, 650-652. PubMed Europe PubMed DOI I -
Sun,X., Wen,X., Chen,Y.Y., Shi,C., Gao,C., Wu,Y., Wang,L.J., Yang,X.H. and Sun,H.
Discovery of highly potent renin inhibitors potentially interacting with the S3' subsite of renin
Eur J Med Chem103, 269-288. PubMed Europe PubMed DOI I -
Fisher,N.D. and Meagher,E.A.
Renin inhibitors
J Clin Hypertens (Greenwich)13, 662-666. PubMed Europe PubMed DOI I -
Kher,V.
Renin inhibition - benefit beyond hypertension control
J Assoc Physicians India57, 518-520. PubMed Europe PubMed I -
Riccioni,G., Vitulano,N., D'Orazio,N. and Bellocci,F.
Aliskiren, the first approved renin inhibitor: clinical application and safety in the treatment of hypertension
Adv Ther26, 700-710. PubMed Europe PubMed DOI I -
Sanoski,C.A.
Aliskiren: an oral direct renin inhibitor for the treatment of hypertension
Pharmacotherapy29, 193-212. PubMed Europe PubMed DOI I -
Dockery,B.K. and Bisognano,J.D.
Direct renin inhibition: an analysis of possible benefits
Curr Hypertens Rep10, 313-318. PubMed Europe PubMed DOI T I -
Jensen,C., Herold,P. and Brunner,H.R.
Aliskiren: the first renin inhibitor for clinical treatment
Nat Rev Drug Discov7, 399-410. PubMed Europe PubMed DOI I -
Dechend,R., Shagdarsuren,E., Gratze,P., Fiebeler,A., Pilz,B., Meiners,S., Derer,W., Feldman,D.L., Webb,R. and Muller,D.N.
Low-dose renin inhibitor and low-dose AT(1)-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes
J Renin Angiotensin Aldosterone Syst8, 81-84. PubMed Europe PubMed DOI I -
Maibaum,J., Stutz,S., Goschke,R., Rigollier,P., Yamaguchi,Y., Cumin,F., Rahuel,J., Baum,H.P., Cohen,N.C., Schnell,C.R., Fuhrer,W., Gruetter,M.G., Schilling,W. and Wood,J.M.
Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets
J Med Chem50, 4832-4844. PubMed Europe PubMed DOI I -
Pool,J.L.
Direct renin inhibition: focus on aliskiren
J Manag Care Pharm13, 21-33. PubMed Europe PubMed I -
Van Tassell,B.W. and Munger,M.A.
Aliskiren for renin inhibition: a new class of antihypertensives
Ann Pharmacother41, 456-464. PubMed Europe PubMed DOI I -
Kalus,J.S.
Aliskiren: a novel oral renin inhibitor for the treatment of hypertension
Formulary41, 631-638. I -
Kushiro,T., Itakura,H., Abo,Y., Gotou,H., Terao,S. and Keefe,D.L.
Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension
Hypertens Res29, 997-1005. PubMed Europe PubMed DOI I -
Luft,F.C.
Achieving the goal of optimised renin system suppression: preclinical experience with a direct renin inhibitor
J Renin Angiotensin Aldosterone Syst7 Suppl 2, S12-S15. I -
Muller,D.N. and Luft,F.C.
Direct renin inhibition with aliskiren in hypertension and target organ damage
Clin J Am Soc Nephrol1, 221-228. PubMed Europe PubMed DOI I -
Staessen,J.A., Li,Y. and Richart,T.
Oral renin inhibitors
Lancet368, 1449-1456. PubMed Europe PubMed DOI I -
[YEAR:1-3-2005]Gradman,A.H., Schmieder,R.E., Lins,R.L., Nussberger,J., Chiang,Y. and Bedigian,M.P.
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
Circulation111, 1012-1018. PubMed Europe PubMed DOI I -
Wood,J.M., Schnell,C.R., Cumin,F., Menard,J. and Webb,R.L.
Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats
J Hypertens23, 417-426. PubMed Europe PubMed DOI I -
[YEAR:5-9-2003]Wood,J.M., Maibaum,J., Rahuel,J., Grutter,M.G., Cohen,N.C., Rasetti,V., Ruger,H., Goschke,R., Stutz,S., Fuhrer,W., Schilling,W., Rigollier,P., Yamaguchi,Y., Cumin,F., Baum,H.P., Schnell,C.R., Herold,P., Mah,R., Jensen,C., O'Brien,E., Stanton,A. and Bedigian,M.P.
Structure-based design of aliskiren, a novel orally effective renin inhibitor
Biochem Biophys Res Commun308, 698-705. PubMed Europe PubMed DOI S I
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