Literature for TLCK (S01.151 inhibitor)

Summary Literature

(Topics flags: S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2014
  1. Reuther,C., Ganjam,G.K., Dolga,A.M. and Culmsee,C.<br>The serine protease inhibitor TLCK attenuates intrinsic death pathways in neurons upstream of mitochondrial demise<br>Apoptosis (2014) 19, 1545-1558. PubMed  Europe PubMed DOI  I
  2. 2009
  3. Ha,K.H., Byun,M.S., Choi,J., Jeong,J., Lee,K.J. and Jue,D.M.<br>N-Tosyl-l-phenylalanine chloromethyl ketone inhibits NF-kappaB activation by blocking specific cysteine residues of IkappaB kinase beta and p65/RelA<br>Biochemistry (2009) 48, 7271-7278. PubMed  Europe PubMed DOI  I
  4. 2008
  5. Frydrych,I. and Mlejnek,P.<br>Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-l-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases<br>J Cell Biochem (2008) 103, 1646-1656. PubMed  Europe PubMed DOI  I
  6. 1996
  7. Stoppler,H., Stoppler,M.C., Adduci,A., Koval,D. and Schlegel,R.<br>The serine protease inhibitors TLCK and TPCK react with the RB-binding core of HPV-18 E7 protein and abolish its RB-binding capability<br>Virology (1996) 217, 542-553. PubMed  Europe PubMed DOI  I
  8. 1990
  9. [YEAR:15-5-1990]Greco,N.J., Tenner,T.E., Jr., Tandon,N.N. and Jamieson,G.A.<br>PPACK-thrombin inhibits thrombin-induced platelet aggregation and cytoplasmic acidification but does not inhibit platelet shape change<br>Blood (15-5-1990) 75, 1989-1990. PubMed  Europe PubMed  I
  10. 1984
  11. [YEAR:23-7-1984]Gilles,A.M. and Keil,B.<br>Evidence for an active-center cysteine in the SH-proteinase alpha-clostripain through use of N-tosyl-L-lysine chloromethyl ketone<br>FEBS Lett (23-7-1984) 173, 58-62. PubMed  Europe PubMed  I
  12. 1983
  13. Malthouse,J.P.G., Mackenzie,N.E., Boyd,A.S.F. and Scott,A.I.<br>Detection of a tetrahedral adduct in a trypsin-chloromethyl ketone specific inhibitor complex by 13C NMR<br>J Am Chem Soc (1983) 105, 1685-1686.  I
  14. 1976
  15. Poulos,T.L., Alden,R.A., Freer,S.T., Birktoft,J.J. and Kraut,J.<br>Polypeptide halomethyl ketones bind to serine proteases as analogs of the tetrahedral intermediate. X-ray crystallographic comparison of lysine- and phenylalanine-polypeptide chloromethyl ketone-inhibited subtilisin<br>J Biol Chem (1976) 251, 1097-1103. PubMed  Europe PubMed  S  I
  16. 1971
  17. Porter,W.H., Cunningham,L.W. and Mitchell,W.M.<br>Studies on the active site of clostripain. The specific inactivation by the chloromethyl ketone derived from alpha-N-tosyl-L-lysine<br>J Biol Chem (1971) 246, 7675-7682. PubMed  Europe PubMed  I
  18. 1969
  19. Smith,R.L. and Shaw,E.<br>Pseudotrypsin. A modified bovine trypsin produced by limited autodigestion<br>J Biol Chem (1969) 244, 4704-4712. PubMed  Europe PubMed  I
  20. Wolthers,B.C.<br>Kinetics of inhibition of papain by TLCK and TPCK in the presence of BAEE as substrate<br>FEBS Lett (1969) 2, 143-145. PubMed  Europe PubMed  I
  21. 1968
  22. [YEAR:20-3-1968]Whitaker,J.R. and Perez-Villase nor,J.<br>Chemical modification of papain. I. Reaction with the chloromethyl ketones of phenylalanine and lysine and with phenylmethyl-sulfonyl fluoride<br>Arch Biochem Biophys (20-3-1968) 124, 70-78. PubMed  Europe PubMed  I
  23. 1967
  24. [YEAR:10-4-1967]Kafatos,F.C., Law,J.H. and Tartakoff,A.M.<br>Cocoonase. II. Substrate specificity, inhibitors, and classification of the enzyme<br>J Biol Chem (10-4-1967) 242, 1488-1494. PubMed  Europe PubMed  I
  25. 1965
  26. [YEAR:21-12-1965]Petra,P.H., Cohen,W. and Shaw,E.N.<br>Isolation and characterization of the alkylated histidine from TLCK inhibited trypsin<br>Biochem Biophys Res Commun (21-12-1965) 21, 612-618. PubMed  Europe PubMed  I
  27. Shaw,E., Mares-Guia,M. and Cohen,W.<br>Evidence for an active-center histidine in trypsin through use of a specific reagent, 1-chloro-3-tosylamido-7-amino-2-heptanone, the chloromethyl ketone derived from Nalpha-tosyl-L-lysine<br>Biochemistry (1965) 4, 2219-2224.  I