Literature for CGS27023A (M10.004 inhibitor)

(Topics flags: S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2015
1. Behrends,M., Wagner,S., Kopka,K., Schober,O., Schafers,M., Kumbhar,S., Waller,M. and Haufe,G.
   New matrix metalloproteinase inhibitors based on gamma-fluorinated alpha-aminocarboxylic and alpha-aminohydroxamic acids
   Bioorg Med Chem23, 3809-3818. PubMed  Europe PubMed DOI  I
2012
2. Kovacs,H., Agback,T. and Isaksson,J.
   Probing water-protein contacts in a MMP-12/CGS27023A complex by nuclear magnetic resonance spectroscopy
   J Biomol NMR53, 85-92. PubMed  Europe PubMed DOI  I
2008
3. Yang,S.M., Scannevin,R.H., Wang,B., Burke,S.L., Wilson,L.J., Karnachi,P., Rhodes,K.J., Lagu,B. and Murray,W.V.
   beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. design, synthesis, and lead identification
   Bioorg Med Chem Lett18, 1135-1139. PubMed  Europe PubMed DOI  I
4. Yang,S.M., Scannevin,R.H., Wang,B., Burke,S.L., Huang,Z., Karnachi,P., Wilson,L.J., Rhodes,K.J., Lagu,B. and Murray,W.V.
   beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents
   Bioorg Med Chem Lett18, 1140-1145. PubMed  Europe PubMed DOI  I
2006
5. [YEAR:14-2-2006]Tuccinardi,T., Martinelli,A., Nuti,E., Carelli,P., Balzano,F., Uccello-Barretta,G., Murphy,G. and Rossello,A.
   Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides
   Bioorg Med Chem14, 4260-4276. PubMed  Europe PubMed DOI  I
2004
6. [YEAR:1-5-2004]Rossello,A., Nuti,E., Orlandini,E., Carelli,P., Rapposelli,S., Macchia,M., Minutolo,F., Carbonaro,L., Albini,A., Benelli,R., Cercignani,G., Murphy,G. and Balsamo,A.
   New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2)
   Bioorg Med Chem12, 2441-2450. PubMed  Europe PubMed DOI  I
2003
7. [YEAR:15-12-2003]Xue,C.B., He,X., Roderick,J., Corbett,R.L., Duan,J.J., Liu,R.Q., Covington,M.B., Newton,R.C., Trzaskos,J.M., Magolda,R.L., Wexler,R.R. and Decicco,C.P.
   Rational design, synthesis and structure-activity relationships of a cyclic succinate series of TNF-alpha converting enzyme inhibitors. Part 1: lead identification
   Bioorg Med Chem Lett13, 4293-4297. PubMed  Europe PubMed DOI  I
2001
8. [YEAR:28-9-2001]Nar,H., Werle,K., Bauer,M.M., Dollinger,H. and Jung,B.
   Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor
   J Mol Biol312, 743-751. PubMed  Europe PubMed DOI  S  I
2000
9. [YEAR:22-9-2000]Moy,F.J., Chanda,P.K., Chen,J.M., Cosmi,S., Edris,W., Levin,J.I. and Powers,R.
   High-resolution solution structure of the catalytic fragment of human collagenase-3 (MMP-13) complexed with a hydroxamic acid inhibitor
   J Mol Biol302, 671-689. PubMed  Europe PubMed DOI  S  I
1999
10. [YEAR:1-6-1999]Moy,F.J., Chanda,P.K., Chen,J.M., Cosmi,S., Edris,W., Skotnicki,J.S., Wilhelm,J. and Powers,R.
    NMR solution structure of the catalytic fragment of human fibroblast collagenase complexed with a sulfonamide derivative of a hydroxamic acid compound
    Biochemistry38, 7085-7096. PubMed  Europe PubMed DOI  S  I
1997
11. MacPherson,L.J., Bayburt,E.K., Capparelli,M.P., Carroll,B.J., Goldstein,R., Justice,M.R., Zhu,L., Hu,S., Melton,R.A., Fryer,L., Goldberg,R.L., Doughty,J.R., Spirito,S., Blancuzzi,V., Wilson,D., O'Byrne,E.M., Ganu,V. and Parker,D.T.
    Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits
    J Med Chem40, 2525-2532. PubMed  Europe PubMed DOI  I