Literature for SCH6 (S29.001 inhibitor)

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2007
1. Liu,R., Abid,K., Pichardo,J., Pazienza,V., Ingravallo,P., Kong,R., Agrawal,S., Bogen,S., Saksena,A., Cheng,K.C., Prongay,A., Njoroge,F.G., Baroudy,B.M. and Negro,F.
   In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease
   J Antimicrob Chemother59, 51-58. PubMed  Europe PubMed DOI  I
2006
2. [YEAR:4-5-2006]Bogen,S.L., Arasappan,A., Bennett,F., Chen,K., Jao,E., Liu,Y.T., Lovey,R.G., Venkatraman,S., Pan,W., Parekh,T., Pike,R.E., Ruan,S., Liu,R., Baroudy,B., Agrawal,S., Chase,R., Ingravallo,P., Pichardo,J., Prongay,A., Brisson,J.M., Hsieh,T.Y., Cheng,K.C., Kemp,S.J., Levy,O.E., Lim-Wilby,M., Tamura,S.Y., Saksena,A.K., Girijavallabhan,V. and Njoroge,F.G.
   Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication
   J Med Chem49, 2750-2757. PubMed  Europe PubMed DOI  I
3. Guo,Z., Prongay,A., Tong,X., Fischmann,T., Bogen,S., Velazquez,F., Venkatraman,S., Njoroge,F.G. and Madison,V.
   Computational study of the effects of mutations A156T, D168V, and D168Q on the binding of HCV protease inhibitors
   J Chem Theory Comput2, 1657-1663. PubMed  Europe PubMed DOI  I
4. [YEAR:13-12-2006]Yi,M., Tong,X., Skelton,A., Chase,R., Chen,T., Prongay,A., Bogen,S.L., Saksena,A.K., Njoroge,F.G., Veselenak,R.L., Pyles,R.B., Bourne,N., Malcolm,B.A. and Lemon,S.M.
   Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations
   J Biol Chem281, 8205-8215. PubMed  Europe PubMed DOI  I
2003
5. [YEAR:16-5-2003]Foy,E., Li,K., Wang,C., Sumpter,R., Jr., Ikeda,M., Lemon,S.M. and Gale,M., Jr.
   Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
   Science300, 1145-1148. PubMed  Europe PubMed DOI  I