Literature for LY2811376 (A01.004 inhibitor)

Summary Literature

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2017
  1. Ellis,C.R., Tsai,C.C., Lin,F.Y. and Shen,J.
    Conformational dynamics of cathepsin D and binding to a small-molecule BACE1 inhibitor
    J Comput Chem38, 1260-1269. PubMed  Europe PubMed DOI  I
  2. 2015
  3. Filser,S., Ovsepian,S.V., Masana,M., Blazquez-Llorca,L., Brandt Elvang,A., Volbracht,C., Muller,M.B., Jung,C.K. and Herms,J.
    Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions
    Biol Psychiatry77, 729-739. PubMed  Europe PubMed DOI  I
  4. 2011
  5. May,P.C., Dean,R.A., Lowe,S.L., Martenyi,F., Sheehan,S.M., Boggs,L.N., Monk,S.A., Mathes,B.M., Mergott,D.J., Watson,B.M., Stout,S.L., Timm,D.E., Smith Labell,E., Gonzales,C.R., Nakano,M., Jhee,S.S., Yen,M., Ereshefsky,L., Lindstrom,T.D., Calligaro,D.O., Cocke,P.J., Greg Hall,D., Friedrich,S., Citron,M. and Audia,J.E.
    Robust central reduction of amyloid-beta in humans with an orally available, non-peptidic beta-secretase inhibitor
    J Neurosci31, 16507-16516. PubMed  Europe PubMed DOI  I