Literature for PF-3084014 (XA22.001 inhibitor)

Summary Literature

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Sobrido-Camean,D., Robledo,D., Romaus-Sanjurjo,D., Perez-Cedron,V., Sanchez,L., Rodicio,M.C. and Barreiro-Iglesias,A.
    Inhibition of gamma-secretase promotes axon regeneration after a complete spinal cord injury
    Front Cell Dev Biol8, 173-173. PubMed  Europe PubMed DOI  I
  2. 2011
  3. Brodney,M.A., Auperin,D.D., Becker,S.L., Bronk,B.S., Brown,T.M., Coffman,K.J., Finley,J.E., Hicks,C.D., Karmilowicz,M.J., Lanz,T.A., Liston,D., Liu,X., Martin,B.A., Nelson,R.B., Nolan,C.E., Oborski,C.E., Parker,C.P., Richter,K.E., Pozdnyakov,N., Sahagan,B.G., Schachter,J.B., Sokolowski,S.A., Tate,B., Wood,D.E., Wood,K.M., Van Deusen,J.W. and Zhang,L.
    Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as gamma-secretase inhibitors: discovery of PF-3084014
    Bioorg Med Chem Lett21, 2637-2640. PubMed  Europe PubMed DOI  I
  4. 2010
  5. Lanz,T.A., Wood,K.M., Richter,K.E., Nolan,C.E., Becker,S.L., Pozdnyakov,N., Martin,B.A., Du,P., Oborski,C.E., Wood,D.E., Brown,T.M., Finley,J.E., Sokolowski,S.A., Hicks,C.D., Coffman,K.J., Geoghegan,K.F., Brodney,M.A., Liston,D. and Tate,B.
    Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014
    J Pharmacol Exp Ther334, 269-277. PubMed  Europe PubMed DOI  I
  6. Wei,P., Walls,M., Qiu,M., Ding,R., Denlinger,R.H., Wong,A., Tsaparikos,K., Jani,J.P., Hosea,N., Sands,M., Randolph,S. and Smeal,T.
    Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design
    Mol Cancer Ther9, 1618-1628. PubMed  Europe PubMed DOI  I