Literature for GRL-98065 (A02.001 inhibitor)

(Topics flags: S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2012
1. Kar,P. and Knecht,V.
   Origin of decrease in potency of darunavir and two related antiviral inhibitors against HIV-2 compared to HIV-1 protease
   J Phys Chem B116, 2605-2614. PubMed  Europe PubMed DOI  I
2010
2. Hu,G.D., Zhu,T., Zhang,S.L., Wang,D. and Zhang,Q.G.
   Some insights into mechanism for binding and drug resistance of wild type and I50V V82A and I84V mutations in HIV-1 protease with GRL-98065 inhibitor from molecular dynamic simulations
   Eur J Med Chem45, 227-235. PubMed  Europe PubMed DOI  I
2008
3. Kovalevsky,A.Y., Louis,J.M., Aniana,A., Ghosh,A.K. and Weber,I.T.
   Structural evidence for effectiveness of darunavir and two related antiviral inhibitors against HIV-2 protease
   J Mol Biol384, 178-192. PubMed  Europe PubMed DOI  S  I
2007
4. Amano,M., Koh,Y., Das,D., Li,J., Leschenko,S., Wang,Y.F., Boross,P.I., Weber,I.T., Ghosh,A.K. and Mitsuya,H.
   A novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI), GRL-98065, is potent against multiple-PI-resistant human immunodeficiency virus in vitro
   Antimicrob Agents Chemother51, 2143-2155. PubMed  Europe PubMed DOI  I
5. Wang,Y.F., Tie,Y., Boross,P.I., Tozser,J., Ghosh,A.K., Harrison,R.W. and Weber,I.T.
   Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease
   J Med Chem50, 4509-4515. PubMed  Europe PubMed DOI  I