Literature for begacestat (XA22.001 inhibitor)

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2008
1. Mayer,S.C., Kreft,A.F., Harrison,B., Abou-Gharbia,M., Antane,M., Aschmies,S., Atchison,K., Chlenov,M., Cole,D.C., Comery,T., Diamantidis,G., Ellingboe,J., Fan,K., Galante,R., Gonzales,C., Ho,D.M., Hoke,M.E., Hu,Y., Huryn,D., Jain,U., Jin,M., Kremer,K., Kubrak,D., Lin,M., Lu,P., Magolda,R., Martone,R., Moore,W., Oganesian,A., Pangalos,M.N., Porte,A., Reinhart,P., Resnick,L., Riddell,D.R., Sonnenberg-Reines,J., Stock,J.R., Sun,S.C., Wagner,E., Wang,T., Woller,K., Xu,Z., Zaleska,M.M., Zeldis,J., Zhang,M., Zhou,H. and Jacobsen,J.S.
   Discovery of begacestat, a notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease
   J Med Chem51, 7348-7351. PubMed  Europe PubMed DOI  I