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Literature for SB-3CT (M10.003, M10.004 inhibitor)

Summary Literature Inhibits

(Topics flags: S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2018
  1. Raz,L., Yang,Y., Thompson,J., Hobson,S., Pesko,J., Mobashery,S., Chang,M. and Rosenberg,G.
    MMP-9 inhibitors impair learning in spontaneously hypertensive rats
    PLoS ONE (2018) 13, e0208357-e0208357. PubMed  Europe PubMed DOI  I
    2. 2017
  2. Du,H.T., Du,L.L., Tang,X.L., Ge,H.Y. and Liu,P.
    Blockade of MMP-2 and MMP-9 inhibits corneal lymphangiogenesis
    Graefes Arch Clin Exp Ophthalmol (2017) 255, 1573-1579. PubMed  Europe PubMed DOI  I
    3. 2016
  3. Gooyit,M., Peng,Z., Mobashery,S. and Chang,M.
    Chapter 10: Thiirane class of gelatinase inhibitors as a privileged template that crosses the blood-brain barrier
    RSC Drug Discov Ser (2016) 2016-January, 262-286. DOI  I
    4. 2015
  4. Lee,M., Chen,Z., Tomlinson,B.N., Gooyit,M., Hesek,D., Juarez,M.R., Nizam,R., Boggess,B., Lastochkin,E., Schroeder,V.A., Wolter,W.R., Suckow,M.A., Cui,J., Mobashery,S., Gu,Z. and Chang,M.
    Water-soluble MMP-9 inhibitor reduces lesion volume after severe traumatic brain injury
    ACS Chem Neurosci (2015) 6, 1658-1664. PubMed  Europe PubMed DOI  I
    5. 2014
  5. Fabre,B., Filipiak,K., Diaz,N., Zapico,J.M., Suarez,D., Ramos,A. and de Pascual-Teresa,B.
    An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily
    Chembiochem (2014) 15, 399-412. PubMed  Europe PubMed DOI  I
  6. Jia,F., Yin,Y.H., Gao,G.Y., Wang,Y., Cen,L. and Jiang,J.Y.
    MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat
    J Neurotrauma (2014) 31, 1225-1234. PubMed  Europe PubMed DOI  I
    7. 2013
  7. Hadass,O., Tomlinson,B.N., Gooyit,M., Chen,S., Purdy,J.J., Walker,J.M., Zhang,C., Giritharan,A.B., Purnell,W., Robinson,C.R.2., Shin,D., Schroeder,V.A., Suckow,M.A., Simonyi,A., Sun,G.Y., Mobashery,S., Cui,J., Chang,M. and Gu,Z.
    Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury
    PLoS ONE (2013) 8, e76904-e76904. PubMed  Europe PubMed DOI  PMC  EPMC  I
    8. 2012
  8. Cui,J., Chen,S., Zhang,C., Meng,F., Wu,W., Hu,R., Hadass,O., Lehmidi,T., Blair,G.J., Lee,M., Chang,M., Mobashery,S., Sun,G.Y. and Gu,Z.
    Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia
    Mol Neurodegener (2012) 7, 21-21. PubMed  Europe PubMed DOI  I
  9. Gooyit,M., Suckow,M.A., Schroeder,V.A., Wolter,W.R., Mobashery,S. and Chang,M.
    Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier
    ACS Chem Neurosci (2012) 3, 730-736. PubMed  Europe PubMed DOI  PMC  EPMC  I
  10. Lee,M., Ikejiri,M., Klimpel,D., Toth,M., Espahbodi,M., Hesek,D., Forbes,C., Kumarasiri,M., Noll,B.C., Chang,M. and Mobashery,S.
    Structure-activity relationship for thiirane-based gelatinase inhibitors
    ACS Med Chem Lett (2012) 3, 490-495. PubMed  Europe PubMed DOI  PMC  EPMC  I
  11. Ranasinghe,H.S., Scheepens,A., Sirimanne,E., Mitchell,M.D., Williams,C.E. and Fraser,M.
    Inhibition of MMP-9 activity following hypoxic ischemia in the developing brain using a highly specific inhibitor
    Dev Neurosci (2012) 34, 417-427. PubMed  Europe PubMed DOI  I
    12. 2011
  12. Benson,H.L., Mobashery,S., Chang,M., Kheradmand,F., Hong,J.S., Smith,G.N., Shilling,R.A. and Wilkes,D.S.
    Endogenous matrix metalloproteinases 2 and 9 regulate activation of CD4+ and CD8+ T cells
    Am J Respir Cell Mol Biol (2011) 44, 700-708. PubMed  Europe PubMed DOI  PMC  EPMC  I
  13. Gooyit,M., Lee,M., Schroeder,V.A., Ikejiri,M., Suckow,M.A., Mobashery,S. and Chang,M.
    Selective water-soluble gelatinase inhibitor prodrugs
    J Med Chem (2011) 54, 6676-6690. PubMed  Europe PubMed DOI  I
  14. Guo,Z.D., Zhang,X.D., Wu,H.T., Lin,B., Sun,X.C. and Zhang,J.H.
    Matrix metalloproteinase 9 inhibition reduces early brain injury in cortex after subarachnoid hemorrhage
    Acta Neurochir Suppl (2011) 110, 81-84. PubMed  Europe PubMed DOI  I
  15. Liu,H. and Shubayev,V.I.
    Matrix metalloproteinase-9 controls proliferation of NG2+ progenitor cells immediately after spinal cord injury
    Exp Neurol (2011) 231, 236-246. PubMed  Europe PubMed DOI  I
  16. Qiu,L.B., Zhou,Y., Wang,Q., Yang,L.L., Liu,H.Q., Xu,S.L., Qi,Y.H., Ding,G.R. and Guo,G.Z.
    Synthetic gelatinases inhibitor attenuates electromagnetic pulse-induced blood-brain barrier disruption by inhibiting gelatinases-mediated ZO-1 degradation in rats
    Toxicology (2011) 285, 31-38. PubMed  Europe PubMed DOI  I
  17. Testero,S.A., Llarrull,L.I., Fisher,J.F., Chang,M. and Mobashery,S.
    Exploring the functional space of thiiranes as gelatinase inhibitors using click chemistry
    Arkivoc (2011) 2011, 221-236.  I
    18. 2010
  18. Tao,P., Fisher,J.F., Shi,Q., Mobashery,S. and Schlegel,H.B.
    Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT
    J Phys Chem B (2010) 114, 1030-1037. PubMed  Europe PubMed DOI  I
  19. Zhou,J., Tao,P., Fisher,J.F., Shi,Q., Mobashery,S. and Schlegel,H.B.
    QM/MM studies of the matrix metalloproteinase 2 (MMP2) inhibition mechanism of (S)-SB-3CT and its oxirane analogue
    J Chem Theory Comput (2010) 6, 3580-3587. PubMed  Europe PubMed DOI  PMC  EPMC  I
    20. 2009
  20. Forbes,C., Shi,Q., Fisher,J.F., Lee,M., Hesek,D., Llarrull,L.I., Toth,M., Gossing,M., Fridman,R. and Mobashery,S.
    Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases
    Chem Biol Drug Des (2009) 74, 527-534. PubMed  Europe PubMed DOI  PMC  EPMC  I
  21. Gooyit,M., Lee,M., Hesek,D., Boggess,B., Oliver,A.G., Fridman,R., Mobashery,S. and Chang,M.
    Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors
    Chem Biol Drug Des (2009) 74, 535-546. PubMed  Europe PubMed DOI  I
  22. Tao,P., Fisher,J.F., Mobashery,S. and Schlegel,H.B.
    DFT studies of the ring-opening mechanism of SB-3CT, a potent inhibitor of matrix metalloproteinase 2
    Org Lett (2009) 11, 2559-2562. PubMed  Europe PubMed DOI  I
  23. Tao,P., Fisher,J.F., Shi,Q., Vreven,T., Mobashery,S. and Schlegel,H.B.
    Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue
    Biochemistry (2009) 48, 9839-9847. PubMed  Europe PubMed DOI  I
  24. Yao,P.L., Lin,Y.C. and Richburg,J.H.
    TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2
    Biol Reprod (2009) 80, 581-589. PubMed  Europe PubMed DOI  PMC  EPMC  I
    25. 2008
  25. Celenza,G., Villegas-Estrada,A., Lee,M., Boggess,B., Forbes,C., Wolter,W.R., Suckow,M.A., Mobashery,S. and Chang,M.
    Metabolism of (4-phenoxyphenylsulfonyl) methylthiirane, a selective gelatinase inhibitor
    Chem Biol Drug Des (2008) 71, 187-196. PubMed  Europe PubMed DOI  I
  26. Kim,D.H., Lilliehook,C., Roides,B., Chen,Z., Chang,M., Mobashery,S. and Goldman,S.A.
    Testosterone-induced matrix metalloproteinase activation is a checkpoint for neuronal addition to the adult songbird brain
    J Neurosci (2008) 28, 208-216. PubMed  Europe PubMed DOI  I
  27. Lee,M., Hesek,D., Shi,Q., Noll,B.C., Fisher,J.F., Chang,M. and Mobashery,S.
    Conformational analyses of thiirane-based gelatinase inhibitors
    Bioorg Med Chem Lett (2008) 18, 3064-3067. PubMed  Europe PubMed DOI  I
  28. Yu,F., Kamada,H., Niizuma,K., Endo,H. and Chan,P.H.
    Induction of MMP-9 expression and endothelial injury by oxidative stress after spinal cord injury
    J Neurotrauma (2008) 25, 184-195. PubMed  Europe PubMed DOI  PMC  EPMC  I
    29. 2007
  29. Lee,M., Villegas-Estrada,A., Celenza,G., Boggess,B., Toth,M., Kreitinger,G., Forbes,C., Fridman,R., Mobashery,S. and Chang,M.
    Metabolism of a highly selective gelatinase inhibitor generates active metabolite
    Chem Biol Drug Des (2007) 70, 371-382. PubMed  Europe PubMed DOI  I
    30. 2006
  30. Bonfil,R.D., Sabbota,A., Nabha,S., Bernardo,M.M., Dong,Z., Meng,H., Yamamoto,H., Chinni,S.R., Lim,I.T., Chang,M., Filetti,L.C., Mobashery,S., Cher,M.L. and Fridman,R.
    Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor
    Int J Cancer (2006) 118, 2721-2726. PubMed  Europe PubMed DOI  I
    31. 2005
  31. [YEAR:6-7-2005]Gu,Z., Cui,J., Brown,S., Fridman,R., Mobashery,S., Strongin,A.Y. and Lipton,S.A.
    A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia
    J Neurosci (6-7-2005) 25, 6401-6408. PubMed  Europe PubMed DOI  I
  32. [YEAR:8-7-2005]Ikejiri,M., Bernardo,M.M., Meroueh,S.O., Brown,S., Chang,M., Fridman,R. and Mobashery,S.
    Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A
    J Org Chem (8-7-2005) 70, 5709-5712. PubMed  Europe PubMed DOI  I
  33. [YEAR:1-5-2005]Kruger,A., Arlt,M.J., Gerg,M., Kopitz,C., Bernardo,M.M., Chang,M., Mobashery,S. and Fridman,R.
    Antimetastatic activity of a novel mechanism-based gelatinase inhibitor
    Cancer Res (1-5-2005) 65, 3523-3526. PubMed  Europe PubMed DOI  I
  34. [YEAR:29-9-2005]Lee,M., Bernardo,M.M., Meroueh,S.O., Brown,S., Fridman,R. and Mobashery,S.
    Synthesis of chiral 2-(4-phenoxyphenylsulfonylmethyl)thiiranes as selective gelatinase inhibitors
    Org Lett (29-9-2005) 7, 4463-4465. PubMed  Europe PubMed DOI  I
    35. 2004
  35. [YEAR:23-7-2004]Solomon,A., Rosenblum,G., Gonzales,P.E., Leonard,J.D., Mobashery,S., Milla,M.E. and Sagi,I.
    Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity
    J Biol Chem (23-7-2004) 279, 31646-31654. PubMed  Europe PubMed DOI  I
    36. 2001
  36. [YEAR:18-5-2001]Kleifeld,O., Kotra,L.P., Gervasi,D.C., Brown,S., Bernardo,M.M., Fridman,R., Mobashery,S. and Sagi,I.
    X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor. Comparison with the latent and active forms of the enzyme
    J Biol Chem (18-5-2001) 276, 17125-17131. PubMed  Europe PubMed DOI  S  I
    37. 2000
  37. Brown,S., Bernardo,M.M., Li,Z.H., Kotra,L.P., Tanaka,Y., Fridman,R. and Mobashery,S.
    Potent and selective mechanism-based inhibition of gelatinases
    J Am Chem Soc (2000) 122, 6799-6800. DOI  I

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