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Literature for inhibitor I47.001: latexin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Inhibits

(Topics flags: S Structure. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Huang,Q., Jin,Y., Song,J., Ul Abideen,Z., Tan,R., Xu,S., Shu,W. and Chen,M.
    Molecular regulation of coagulation by heparin-bound plasma Latexin
    Int J Biol Macromol (2026) 335, 149233-149233. PubMed  Europe PubMed DOI
    2. 2025
  2. Adeluola,A.A., Hossain,M.S. and Amin,A.R.M.R.
    Carboxypeptidase A4: A Biomarker for Cancer Aggressiveness and Drug Resistance
    Cancers (Basel) (2025) 17 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2022
  3. Kan,S., Li,R., Tan,Y., Yang,F., Xu,S., Wang,L., Zhang,L., Sun,X., Chen,X., Yang,Y., Shu,W., Wan,H., Chen,Z.F., Liang,H. and Chen,M.
    Latexin deficiency attenuates adipocyte differentiation and protects mice against obesity and metabolic disorders induced by high-fat diet
    Cell Death Dis (2022) 13, 175-175. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2020
  4. Li,Y., Huang,B., Yang,H., Kan,S., Yao,Y., Liu,X., Pu,S., He,G., Khan,T.M., Qi,G., Zhou,Z., Shu,W. and Chen,M.
    Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-kappaB pathway
    Sci Rep (2020) 10, 9868-9868. PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2012
  5. Liu,Y., Howard,D., Rector,K., Swiderski,C., Brandon,J., Schook,L., Mehta,J., Bryson,J.S., Bondada,S. and Liang,Y.
    Latexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth
    PLoS ONE (2012) 7, e44979-e44979. PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2011
  6. Li,Y., Basang,Z., Ding,H., Lu,Z., Ning,T., Wei,H., Cai,H. and Ke,Y.
    Latexin expression is downregulated in human gastric carcinomas and exhibits tumor suppressor potential
    BMC Cancer (2011) 11, 121-121. PubMed  Europe PubMed DOI
    7. 2007
  7. de Haan,G.
    Latexin is a newly discovered regulator of hematopoietic stem cells
    Nat Genet (2007) 39, 141-142. PubMed  Europe PubMed DOI
  8. Pallares,I., Berenguer,C., Aviles,F.X., Vendrell,J. and Ventura,S.
    Self-assembly of human latexin into amyloid-like oligomers
    BMC Struct Biol (2007) 7, 75-75. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2006
  9. [YEAR:7-2-2006]Jin,M., Ishida,M., Katoh-Fukui,Y., Tsuchiya,R., Higashinakagawa,T., Ikegami,S. and Arimatsu,Y.
    Reduced pain sensitivity in mice lacking latexin, an inhibitor of metallocarboxypeptidases
    Brain Res (7-2-2006) 1075, 117-121. PubMed  Europe PubMed DOI
  10. [YEAR:25-10-2006]Mouradov,D., Craven,A., Forwood,J.K., Flanagan,J.U., Garcia-Castellanos,R., Gomis-Ruth,F.X., Hume,D.A., Martin,J.L., Kobe,B. and Huber,T.
    Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking
    Protein Eng Des Sel (25-10-2006) 19, 9-16. PubMed  Europe PubMed DOI
    11. 2005
  11. Aagaard,A., Listwan,P., Cowieson,N., Huber,T., Ravasi,T., Wells,C.A., Flanagan,J.U., Kellie,S., Hume,D.A., Kobe,B. and Martin,J.L.
    An inflammatory role for the mammalian carboxypeptidase inhibitor latexin: relationship to cystatins and the tumor suppressor TIG1
    Structure (2005) 13, 309-317. PubMed  Europe PubMed DOI  S
  12. [YEAR:9-8-2005]Garcia-Castellanos,R., Bonet-Figueredo,R., Pallares,I., Ventura,S., Aviles,F.X., Vendrell,J. and Gomis-Ruth,F.X.
    Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin
    Cell Mol Life Sci (9-8-2005) 62, 1996-2014. PubMed  Europe PubMed DOI
  13. [YEAR:15-3-2005]Pallares,I., Bonet,R., Garcia-Castellanos,R., Ventura,S., Aviles,F.X., Vendrell,J. and Gomis-Ruth,F.X.
    Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin
    Proc Natl Acad Sci U S A (15-3-2005) 102, 3978-3983. PubMed  Europe PubMed DOI  PMC  EPMC  S
    14. 2000
  14. Liu,Q., Yu,L., Gao,J., Fu,Q., Zhang,J., Zhang,P., Chen,J. and Zhao,S.
    Cloning, tissue expression pattern and genomic organization of latexin, a human homologue of rat carboxypeptidase A inhibitor
    Mol Biol Rep (2000) 27, 241-246. PubMed  Europe PubMed DOI
  15. [YEAR:15-3-2000]Uratani,Y., Takiguchi-Hayashi,K., Miyasaka,N., Sato,M., Jin,M. and Arimatsu,Y.
    Latexin, a carboxypeptidase A inhibitor, is expressed in rat peritoneal mast cells and is associated with granular structures distinct from secretory granules and lysosomes
    Biochem J (15-3-2000) 346, 817-826. PubMed  Europe PubMed DOI  PMC  EPMC
    16. 1999
  16. Arimatsu,Y., Ishida,M., Takiguchi-Hayashi,K. and Uratani,Y.
    Cerebral cortical specification by early potential restriction of progenitor cells and later phenotype control of postmitotic neurons
    Development (1999) 126, 629-638. PubMed  Europe PubMed
  17. Arimatsu,Y., Kojima,M. and Ishida,M.
    Area- and lamina-specific organization of a neuronal subpopulation defined by expression of latexin in the rat cerebral cortex
    Neuroscience (1999) 88, 93-105. PubMed  Europe PubMed DOI
  18. Arimatsu,Y., Ishida,M., Sato,M. and Kojima,M.
    Corticocortical associative neurons expressing latexin: specific cortical connectivity formed in vivo and in vitro
    Cereb Cortex (1999) 9, 569-576. PubMed  Europe PubMed DOI
  19. [YEAR:21-5-1999]Miyasaka,N., Hatanaka,Y., Jin,M. and Arimatsu,Y.
    Genomic organization and regulatory elements of the rat latexin gene, which is expressed in a cell type-specific manner in both central and peripheral nervous systems
    Brain Res Mol Brain Res (21-5-1999) 69, 62-72. PubMed  Europe PubMed DOI
    20. 1998
  20. [YEAR:12-3-1998]Arimatsu,Y. and Ishida,M.
    Early patterning of the rat cerebral wall for regional organization of a neuronal population expressing latexin
    Brain Res Dev Brain Res (12-3-1998) 106, 71-78. PubMed  Europe PubMed DOI
  21. [YEAR:10-8-1998]Takiguchi-Hayashi,K., Sato,M., Sugo,N., Ishida,M., Sato,K., Uratani,Y. and Arimatsu,Y.
    Latexin expression in smaller diameter primary sensory neurons in the rat
    Brain Res (10-8-1998) 801, 9-20. PubMed  Europe PubMed DOI
    22. 1997
  22. [YEAR:1-2-1997]Jin,M., Uratani,Y. and Arimatsu,Y.
    Mapping to mouse chromosome 3 of the gene encoding latexin (Lxn) expressed in neocortical neurons in a region-specific manner
    Genomics (1-2-1997) 39, 419-421. PubMed  Europe PubMed DOI
    23. 1995
  23. Normant,E., Martres,M.P., Schwartz,J.C. and Gros,C.
    Purification, cDNA cloning, functional expression, and characterization of a 26-kDa endogenous mammalian carboxypeptidase inhibitor
    Proc Natl Acad Sci U S A (1995) 92, 12225-12229. PubMed  Europe PubMed DOI  PMC  EPMC
  24. [YEAR:26-1-1995]Takiguchi-Hayashi,K. and Arimatsu,Y.
    Restricted expression of latexin in dorsal midline cells of developing rat forebrain
    Neuroreport (26-1-1995) 6, 281-283. PubMed  Europe PubMed
    25. 1994
  25. Arimatsu,Y.
    Latexin: a molecular marker for regional specification in the neocortex
    Neurosci Res (1994) 20, 131-135. PubMed  Europe PubMed DOI
  26. [YEAR:1-6-1994]Hatanaka,Y., Uratani,Y., Takiguchi-Hayashi,K., Omori,A., Sato,K., Miyamoto,M. and Arimatsu,Y.
    Intracortical regionality represented by specific transcription for a novel protein, latexin
    Eur J Neurosci (1-6-1994) 6, 973-982. PubMed  Europe PubMed DOI

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